# Administrative Core

> **NIH NIH P01** · UNIVERSITY OF WISCONSIN-MADISON · 2020 · $286,762

## Abstract

Admin Core - Project Summary/Abstract
The rapid and explosive spread of Zika virus has lead to the recognition that infection during pregnancy
can lead to congenital Zika syndrome. The key hypothesis of this Program Project is that prolonged
maternal viremia during pregnancy predicts the risk of congenital Zika syndrome. We will explore this
hypothesis through three integrated projects. The Administrative (Admin) Core is charged with coordi-
nating activities of the entire Program Project to ensure timely and efficient completion of the overall
scientific goals. The activities of the Admin Core are broadly divided into five Specific Aims:
 Specific Aim 1. Coordinating communications between all participants.
 Specific Aim 2. Ensuring and maintaining regulatory compliance.
 Specific Aim 3. Managing program finances and overseeing subawards.
 Specific Aim 4. Enforcing policies pertaining to scientific rigor, transparency, data sharing, and con-
 flict resolution.
 Specific Aim 5. Promoting professional development of students and junior scientists participating in
 this Program Project.
ZIKV is dangerous to pregnant women and their fetuses/neonates throughout the Americas. This risk
will persist for at least several years, even if it is eventually curtailed by natural immunity and widespread
vaccination. The Admin Core will coordinate all the Projects to ensure completion of all the scientific
goals, providing important new tools for pregnant women and their healthcare providers to assess, and
potentially reduce, the risk of congenital Zika syndrome.

## Key facts

- **NIH application ID:** 9983563
- **Project number:** 5P01AI132132-03
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **Principal Investigator:** David H. O'Connor
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $286,762
- **Award type:** 5
- **Project period:** 2018-08-01 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9983563

## Citation

> US National Institutes of Health, RePORTER application 9983563, Administrative Core (5P01AI132132-03). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9983563. Licensed CC0.

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