# Translational and Precision Medicine Resources Core (TRAP)

> **NIH NIH P30** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2020 · $247,619

## Abstract

TRAP CORE ABSTRACT 
The Translational and Precision Medicine Resources Core (TRAP) core was developed to expedite the 
translation of findings derived from basic science/bench research into novel therapies, by providing 
investigators with the services needed to advance into the translational and clinical realm. In addition, the 
services provided will allow non-dermatologist physicians to appropriately address concerns specific to 
cutaneous diseases that may be relevant to research in both primary cutaneous disorders, or disorders of 
other organ systems with cutaneous manifestations, or cutaneous reactions to therapies.Precision medicine is 
inextricably linked to the continued advance of state of the art research and medical care. The TRAP will offer 
cutting edge approaches to assist investigators in biomarker discovery, assessment and validation. We will 
provide sophisticated computational analysis, bioinformatics and data management to drive the movement of 
novel biomarkers into the realm of clinical use for individual based/personalized risk assessment, monitoring of 
progression or disease, or predicting response to treatment. The TRAP will bridge the gap between bench and 
clinic with four strategic Services, each designed to address a particular barrier to translation. First, the TRAP 
will provide study design and biostatistical expertise in the development of pre-clinical and clinical studies. 
Next, the TRAP will offer services for the ascertainment and procurement of cutaneous tissue and hair follicle 
samples, a critical resource that has been in high demand at our institution, and we expect will be extensively 
utilized by resource community members. We will provide links to the National Alopecia Areata Registry 
Database, thereby allowing access to several thousand individuals who have given consent to be re-contacted 
for additional research in AA. Further, we will provide expert consultations in identifying genomic and 
molecular biomarkers that have the capability to predict or quantify treatment responses, as well as the 
bioinformatic and statistical guidance to glean useful biological insights from raw data generated from 
advanced genomic and molecular tools.

## Key facts

- **NIH application ID:** 9984282
- **Project number:** 5P30AR069632-05
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Julian M. Mackay-Wiggan
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $247,619
- **Award type:** 5
- **Project period:** 2016-08-01 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9984282

## Citation

> US National Institutes of Health, RePORTER application 9984282, Translational and Precision Medicine Resources Core (TRAP) (5P30AR069632-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9984282. Licensed CC0.

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