# Molecular Imaging and Media Core

> **NIH NIH P20** · UNIVERSITY OF NEVADA RENO · 2020 · $74,643

## Abstract

PROJECT SUMMARY/ABSTRACT
Molecular Imaging and Media Core
The Molecular Imaging and Media and Microscopy (Core D) was established in the 4th year of Phase I, and
has directly benefited two COBRE project investigators and other faculty and students using basic molecular
approaches at UNR. The core will be directed and managed by Dr. Alexander van der Linden (graduated
COBRE project leader), and will provide infrastructure, training and equipment required for the high quality
analysis of biomolecules, media and sample preparation resources, and microscopy. The core houses a
Biorad V3 Chemidoc and a GE Typhoon FLA7000 IP imager that allow high-resolution digital imaging of DNA,
RNA, protein and dyes by means of, for instance, chemiluminescence and radio isotopic labels. The core also
houses two Biorad CFX96 Real-Time PCRs for detection and quantification of gene transcript levels. In
addition, the core houses an Integra Mediaclave 10 coupled to a dispenser and other accessories that allow
preparation of food and media for Drosophila and C. elegans research. The main goal of this core in phase II is
to further enhance the scope and quality of basic research by providing workshops, training and technical
expertise of core instruments to users. The core in phase II will also establish a new centralized facility for
husbandry and maintenance of Drosophila, which will directly promote the research of 5 research groups
including two COBRE project leaders. The core in phase II will be expanded to provide training and support to
a shared confocal microscope in the Biology Department, which will be co-managed by the Neuro COBRE and
Cell Biology COBRE. Moreover, as part of an institutional commitment, the core in phase II will be expanded
with a Laser Capture Microdissection scope for isolating specific cells from heterogenous cell populations,
allowing downstream single-cell analysis of DNA, RNA and protein. Taken together, the core will directly
support the aims of two COBRE projects and enhance the scope and quality of 7 additional research groups
within the Biology Department as well as other UNR investigators.

## Key facts

- **NIH application ID:** 9984408
- **Project number:** 5P20GM103650-09
- **Recipient organization:** UNIVERSITY OF NEVADA RENO
- **Principal Investigator:** Alexander Martinus Van der Linden
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $74,643
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9984408

## Citation

> US National Institutes of Health, RePORTER application 9984408, Molecular Imaging and Media Core (5P20GM103650-09). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9984408. Licensed CC0.

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