# PrEP delivery systems for Black men who have sex with men (BMSM) transitioning from jail to community contexts

> **NIH NIH R21** · UNIVERSITY OF CHICAGO · 2020 · $202,500

## Abstract

PROJECT SUMMARY/ABSTRACT
The purpose of this multi-method implementation science study called Justice-PrEP (J-PrEP) is
to examine the current HIV Pre-exposure prophylaxis (PrEP) care landscape and identify
opportunities for PrEP scale-out in jail settings for HIV-uninfected Black men who have sex with
men (BMSM) who are impacted by dual epidemics of HIV and incarceration. We will utilize the
Exploration phase of the Exploration, Preparation, Implementation, and Sustainment (EPIS)
framework as a guide to inform data collection, analysis, and interpretation. We seek to identify
gaps and opportunities to deliver conventional PrEP (i.e., oral PrEP daily dosing based on
current CDC guidelines) and non-conventional PrEP (e.g., on-demand, same day start, directly
observed therapy) forms of PrEP in jails and prior to release for jail-involved BMSM. The study
will be conducted in two diverse contexts with high HIV rates (i.e., Chicago and Baton Rouge). It
will be led by a team of investigators at the University of Chicago in collaboration with
community partners and a Scientific Advisory Group.
Aim 1: Determine awareness, acceptability, and early adoption of conventional and non-
conventional forms of PrEP among jail-involved HIV-uninfected BMSM using the Exploration
phase of the EPIS framework. To accomplish this aim, we will: (1) leverage an existing cohort of
HIV-uninfected BMSM (N=450) by adding jail specific items to the survey in order to determine
estimates for awareness, acceptability, and early adoption of conventional and non-conventional
forms of PrEP in jail context; and (2) conduct in-depth interviews with N=60 jail-involved HIV-
uninfected BMSM (n=30 in each city) to provide rich contextual data.
Aim 2: Examine awareness, acceptability, appropriateness, and feasibility of implementing
conventional and non-conventional forms of PrEP within jail settings from the perspective of
justice-involved stakeholders using the Exploration phase of the EPIS framework. To
accomplish this Aim, we will conduct in-depth interviews with 30 justice-involved stakeholders
(n=15 in each city) to assess: a) their awareness and perceptions about conventional and non-
conventional forms of PrEP delivery; b) potential fit within their agency; c) how PrEP is currently
implemented or how the various forms of PrEP could be implemented; and d) the resources
(e.g., staff, training, cost) required to implement the various forms of PrEP in jail and prior to
release. Study findings will be used to inform the development of a future multi-city study
advancing the Preparation and Implementation phases of the EPIS framework as we scale-out
PrEP implementation in jail settings for HIV-uninfected BMSM.

## Key facts

- **NIH application ID:** 9984542
- **Project number:** 5R21MH121187-02
- **Recipient organization:** UNIVERSITY OF CHICAGO
- **Principal Investigator:** Russell Brewer
- **Activity code:** R21 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $202,500
- **Award type:** 5
- **Project period:** 2019-08-01 → 2023-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9984542

## Citation

> US National Institutes of Health, RePORTER application 9984542, PrEP delivery systems for Black men who have sex with men (BMSM) transitioning from jail to community contexts (5R21MH121187-02). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/9984542. Licensed CC0.

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