# Mass Spectrometric Analytical Collaborations with Members of the Carcinogenesis and Chemoprevention Program of the University of Minnesota Masonic Cancer Center

> **NIH NIH R50** · UNIVERSITY OF MINNESOTA · 2020 · $169,151

## Abstract

ABSTRACT
I manage the mass spectrometry laboratory of the Analytical Biochemistry Shared Resource, Masonic Cancer
Center, University of Minnesota, a National Cancer Institute-designated Comprehensive Cancer Center, which
has emerged as one of the leading academic mass spectrometry laboratories in the U.S. The laboratory is
effectively an extension of the Carcinogenesis and Chemoprevention Program (CCP) of the Masonic Cancer
Center, providing critical analytical services to the members of the program who account for a large majority of
the analysis performed in the facility. The scientific goals of the CCP are to understand the chemical and
molecular mechanisms of carcinogenesis and use this knowledge to develop and evaluate practical methods
for cancer prevention. There are currently 14 NCI-funded projects by CCP members who use the mass
spectrometry facility. The integration of the Analytical Biochemistry Shared Resource and the CCP is such that
the mass spectrometry laboratory staff, through extensive training and consultation with group members and
collaboration with principal investigators, functions as the analytical component of many of the research
groups.
I am an integral part of the CCP through extensive consultation and collaboration with the members regarding
their mass spectrometry-based analyses, as well as working very closely with their research groups. I have
daily interactions with the investigators and routinely attend laboratory group meetings, contribute to writing
manuscripts, and participate in the Carcinogenesis and Chemoprevention Seminar Series and the
Translational Biomarkers Working Group. The need for my consultation and collaboration with members of the
CCP regarding advanced analytical measurement, as well as day-to-day training and oversight of members of
their research groups, has been steadily growing with the increasing analytical capabilities of the laboratory
and the increasing dependency of the users on mass spectrometric analysis to advance their research. In
addition, there is an ongoing need to continue to advance the analytical capabilities of the facility as the field of
biomedical mass spectrometry continues to grow and the research goals of the program members evolve. An
external source of financial support would give me the independence and freedom to focus my efforts on
providing the NCI-funded members of the CCP, as well as other members of the Masonic Cancer Center, with
the support they need to harness the advanced analytical capabilities of the mass spectrometry laboratory.

## Key facts

- **NIH application ID:** 9984983
- **Project number:** 5R50CA211256-05
- **Recipient organization:** UNIVERSITY OF MINNESOTA
- **Principal Investigator:** Peter William Villalta
- **Activity code:** R50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $169,151
- **Award type:** 5
- **Project period:** 2016-09-16 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9984983

## Citation

> US National Institutes of Health, RePORTER application 9984983, Mass Spectrometric Analytical Collaborations with Members of the Carcinogenesis and Chemoprevention Program of the University of Minnesota Masonic Cancer Center (5R50CA211256-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9984983. Licensed CC0.

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