# Genomics Shared Service

> **NIH NIH P30** · UNIVERSITY OF MARYLAND BALTIMORE · 2020 · $83,410

## Abstract

9.0 Abstract: Genomics Shared Service
The mission of the Genomics Shared Service (GSS) is to provide cutting-edge genomic resources designed to
empower high-impact cancer research at UMGCC. The GSS is a comprehensive resource that supports
analysis of chromosomal abnormalities by karyotyping, cytogenomic array, and fluorescence in situ
hybridization; gene expression profiling through microarray and RNAseq methodologies; and identification of
sequence variation through Sanger-based and next-generation sequencing. Genomic resources support basic
research and, through a College of American Pathologists–accredited lab environment that fosters clinical
research, clinical trials and ultimately clinical care. The GSS spectrum of capabilities and expertise allows
investigators a unique opportunity to make basic research discoveries and translate them into clinical care.
Interactions between the GSS and other UMGCC shared services create comprehensive, seamless pipelines
to facilitate access for UMGCC members. GSS staff members, who possess the expertise to help users define
and refine study designs, interact with users to assess their research needs and provide appropriate expertise.
These discussions often include consults with experts from the Biostatistics Shared Service. The GSS interacts
extensively with other UMGCC shared services to obtain and process biospecimens and to analyze large,
high-dimensional datasets resulting from genomic studies. Dr. Ambulos, director of GSS, is also UMGCC
associate director for Shared Services. He ensures streamlined access by UMGCC members.
The GSS is highly utilized. In 2014, it supported studies by 84 Cancer Center members (33 percent of all
UMGCC members), spanning all 5 research programs; 49 percent of UMGCC users have peer-reviewed
funding. The GSS supports many cancer-related publications annually, including papers in high-impact
journals such as Proceedings of the National Academy of Sciences of the United States of America, Science,
Science Translational Medicine, Nature Communications, Cancer Research, and JAMA.

## Key facts

- **NIH application ID:** 9984992
- **Project number:** 5P30CA134274-13
- **Recipient organization:** UNIVERSITY OF MARYLAND BALTIMORE
- **Principal Investigator:** Nicholas P Ambulos
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $83,410
- **Award type:** 5
- **Project period:** 2008-08-08 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9984992

## Citation

> US National Institutes of Health, RePORTER application 9984992, Genomics Shared Service (5P30CA134274-13). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9984992. Licensed CC0.

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