# Pathology and Biorepository Shared Service

> **NIH NIH P30** · UNIVERSITY OF MARYLAND BALTIMORE · 2020 · $88,650

## Abstract

11.0 Abstract: Pathology and Biorepository Shared Service
The mission of the Pathology and Biorepository Shared Service (PBSS) is to maintain and provide
investigators with access to an extensive catalog of patient tissue samples and to make available
pathology/histology services and consultation. The PBSS provides access to a high-quality bank of stored
patient samples (tissue and other preparations) while maintaining patient confidentiality. This permits individual
UMGCC investigators to perform genomic, proteomic, and other studies aimed at understanding the biology of
normal and diseased tissues with an ultimate goal of translating this knowledge into diagnostic and clinical
applications. The PBSS also provides high-quality pathology, histology, and histotechnology consultation
services to assist investigators in procurement, analyses, and clinicopathologic characterization of cancer
specimens. This is the sole tissue bank shared service for specimens removed at surgery on the campus. The
PBSS has developed a close and fruitful working relationship with the Anatomic Pathology Division of the
Department of Pathology, which facilitates the ability of the PBSS to obtain well-characterized tissue samples
and pathology and histology expertise. The PBSS frozen tissue archive consists of over 7,000 frozen tumor
samples, 5,900 of which are paired with normal tissue from the same patient, and over 1,260,000 formalin-
fixed, paraffin-embedded tissue blocks with various pathologic diagnoses obtained at the University of
Maryland Medical Center from 1991 to present. The database for these samples contains patient demographic,
epidemiologic, pathologic, and followup information.
In 2014, the PBSS supported 48 Cancer Center members spanning all 5 research programs (19 percent of all
UMGCC members), 54 percent of whom have peer-reviewed funding. The PBSS supports many cancer-
related publications annually, many in high-impact journals including Clinical Cancer Research, Journal of
Clinical Investigation, and Blood.

## Key facts

- **NIH application ID:** 9984995
- **Project number:** 5P30CA134274-13
- **Recipient organization:** UNIVERSITY OF MARYLAND BALTIMORE
- **Principal Investigator:** Olga Ioffe
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $88,650
- **Award type:** 5
- **Project period:** 2008-08-08 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9984995

## Citation

> US National Institutes of Health, RePORTER application 9984995, Pathology and Biorepository Shared Service (5P30CA134274-13). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/9984995. Licensed CC0.

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