# Training In Cell and Gene Therapy

> **NIH NIH T32** · BAYLOR COLLEGE OF MEDICINE · 2020 · $377,268

## Abstract

PROJECT SUMMARY
This application from the Center for Cell and Gene Therapy (CAGT) / Baylor College of Medicine (BCM)
describes a comprehensive training program in cellular and genetic therapies, for both graduate students and
postdoctoral fellows. This burgeoning area of translational research remains deficient in comprehensive
training schemes for individuals who wish to address basic and clinical translational aspects using these
biological agents. A stimulating program of education and laboratory training from high quality mentors should
continue to attract promising candidates, including under-represented minorities, to this emerging field and
increase the likelihood that they will pursue careers as translational researchers. Translation of basic research
discoveries to clinical practice has become increasingly complex, such that advances in basic research can
only be efficiently implemented when teams of investigators collaborate to validate these novel strategies in the
clinic. This type of translational research training requires a dedicated team of mentors with diverse but
complementary skills. The proposed training exploits the outstanding biomedical curricula and experienced
faculty within BCM and CAGT. A cadre of 27 faculty members with research interests that include vector
design and targeting, stem cell biology, molecular and cellular genetics, immunotherapy, gene therapy and
stem cell transplantation will be available to mentor graduate students and both MD and PhD postdoctoral
fellows. Major strengths of the program are; (1) targeting of rigorous basic biomedical science and clinical
research training toward a translational goal; (2) established and multilevel integration with the proven scientific
excellence of cell biology and genetics research training programs at BCM; (3) involvement of mentors,
including program director and co directors, who have a wealth of experience in translational research and in
training young investigators (4) availability of unique resources such as the GMP laboratories for training.
Augmenting the formal course work and laboratory training will be opportunities to present recent research
findings at annual retreats sponsored by CAGT and academic departments within BCM. During the first 13
years of funding, this approach has successfully trained 25 graduate students who have completed their PhD
degrees: all remain in science careers. Twenty-two postdoctoral fellows have also completed training in
translational cell and gene therapy research and all remain in the field with 15 appointed to academic positions
and 7 in biotechnology. Of all trainees who have completed training or who are still in training 15 are under-
represented minorities with 9 Hispanic, 4 African American, 1 American Indian and 1 African American and
American Indian. All positions on this T32 have been filled at all times and we request an increase in support to
enable us to meet the needs of trainees to provide a strong foundation...

## Key facts

- **NIH application ID:** 9985159
- **Project number:** 5T32HL092332-18
- **Recipient organization:** BAYLOR COLLEGE OF MEDICINE
- **Principal Investigator:** HELEN E HESLOP
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $377,268
- **Award type:** 5
- **Project period:** 2003-07-01 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9985159

## Citation

> US National Institutes of Health, RePORTER application 9985159, Training In Cell and Gene Therapy (5T32HL092332-18). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9985159. Licensed CC0.

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