# 2020 Cardiac Regulatory Mechanisms Gordon Research Conference and Gordon Research Seminar

> **NIH NIH R13** · GORDON RESEARCH CONFERENCES · 2020 · $30,000

## Abstract

Project Summary:
Over the past decade, advances in early detection and diagnosis have begun to reveal the vast complexity of
the primary etiologies that drive pathogenic cardiac remodeling and result in end-stage heart disease; an
enduring health burden in the United States and throughout the world. While current treatments focus on the
late stages of disease, where morphology, function and outcomes are often highly similar, there is growing
evidence that improving patient care and management will require coupling early diagnoses to specific, targeted
therapies that alter the natural history of these progressive and often devastating disorders. The development of
these targeted therapies will require new ideas, new methodologies and new collaborations between basic and
clinical scientists from disparate fields of cardiovascular research. The 2020 Gordon Research Conference
(GRC) on Cardiac Regulatory Mechanisms is the premier conference centered on the fundamental, basic
mechanisms that control normal cardiac function and how these systems are precisely altered in the context of
pathogenic processes, resulting in a broad range of cardiovascular disease states. The 2020 GRC and its
integrated Gordon Research Seminar (GRS) is organized by and for early career scientists and will focus on
how the discovery of fundamental molecular processes that can be leveraged for therapeutic intervention using
approaches that encompass multiple levels of experimental resolution, hence the subtitle “Towards the
Development of Targeted Therapies”. The subjects included in the program cover the latest advances in
understanding cardiac function/dysfunction in the areas of heart failure, inflammation, post-chemotherapy,
calcium regulation, metabolic regulation and myocellular structural dynamics. The main objectives of the
GRC/GRS are 1) to disseminate the latest information and technological advances in Cardiac Regulatory
Mechanisms pertinent to novel therapeutic interventions for heart disease; 2) to engage, motivate and mentor
the next generation of basic and physician-scientists in cardiovascular research and 3) to stimulate collaboration
and multidisciplinary communication in an inclusive environment unique to the Gordon Research Conferences,
which features rigorous discussions of unpublished, controversial or paradigm–challenging data.

## Key facts

- **NIH application ID:** 9986304
- **Project number:** 1R13HL152732-01
- **Recipient organization:** GORDON RESEARCH CONFERENCES
- **Principal Investigator:** Jil C Tardiff
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $30,000
- **Award type:** 1
- **Project period:** 2020-05-01 → 2022-07-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9986304

## Citation

> US National Institutes of Health, RePORTER application 9986304, 2020 Cardiac Regulatory Mechanisms Gordon Research Conference and Gordon Research Seminar (1R13HL152732-01). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9986304. Licensed CC0.

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