# University of Alabama at Birmingham: Pelvic Floor Disorders Network

> **NIH NIH UG1** · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2020 · $222,670

## Abstract

Project Summary/Abstract
As a vanguard center in this important multisite clinical research infrastructure we have demonstrated our
credible, creative, productive, multidisciplinary clinical approach, to the evaluation and treatment, both
surgically and non-surgically, of women with pelvic floor disorders including urinary and fecal incontinence,
pelvic organ prolapse and other sensory and emptying abnormalities of the lower urinary and gastrointestinal
tracts. We have a well-established research and multi-disciplinary clinical infrastructure including long-standing
clinical and research relationships with urology, radiology, geriatrics, behavioral medicine, colorectal surgery,
gastroenterology, maternal fetal medicine, advanced practice nursing, basic sciences and epidemiology and
extensive experience in performing relevant clinical trials and observational studies both within and outside the
PFDN Network. We have substantially contributed to the Network activities by participating at all levels of
clinical trial design, implementation, recruitment, intervention implementation, retention and scientific reporting
and have an excellent track record of facilitation and cooperation with other network sites, the Data
Coordinating Center, Advisory and Data Safety Monitoring Boards. Our site was the first to propose the
addition of a translational aim a priori which served to complement the clinical component of an index trial
(ROSETTA Urinary Marker Study-RUM). We have reported outcomes and implications for care of these
research initiatives at national and international scientific meetings and we are committed to continuing these
activities. In this application we wish to highlight our ability and continued commitment to perform these
meaningful research activities with the result of increasing understanding of the best evidence-based
approaches to the care of women with these disorders.

## Key facts

- **NIH application ID:** 9986460
- **Project number:** 5UG1HD041261-20
- **Recipient organization:** UNIVERSITY OF ALABAMA AT BIRMINGHAM
- **Principal Investigator:** Holly E Richter
- **Activity code:** UG1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $222,670
- **Award type:** 5
- **Project period:** 2001-09-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9986460

## Citation

> US National Institutes of Health, RePORTER application 9986460, University of Alabama at Birmingham: Pelvic Floor Disorders Network (5UG1HD041261-20). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9986460. Licensed CC0.

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