# Core 2: Histopathology and Biospecimen Core

> **NIH NIH P50** · FRED HUTCHINSON CANCER RESEARCH CENTER · 2020 · $350,195

## Abstract

Project Summary/Abstract – Histopathology and Biospecimen Core 
The Histopathology and Biospecimen Core (HBC) represents an integral component of the Fred Hutchinson 
Cancer Research Center (FHCRC) lung cancer SPORE, supporting the translational goals of the Projects as 
well as future SPORE-funded development projects. The mission of the HBC is to facilitate discovery and rapid 
translation of discoveries into clinical care. To this end, the HBC manages the acquisition, annotation, 
processing and distribution of biospecimens from patient-derived and SPORE-funded experimental mouse 
models. The HBC partners with NWBioTrust (NWBT), and Fred Hutchinson/University of Washington Cancer 
Consortium (CCSG) – a funded collaborative resource for obtaining high-quality, well-annotated and 
appropriately-consented and de-identified biospecimens for innovative research. In addition to biobanking 
activities, the HBC is responsible the for managing the performance of downstream tissue-based assays, 
leveraging a suite of cutting-edge histopathologic and imaging capabilities supported by the Fred Hutchinson 
Cancer Research Center (FHCRC) in its extensive network of Shared Resources. These capabilities include, 
but are not limited to, routine histopathologic services, pathology review and consultation, immunohistochemistry 
(IHC), branch-chain in-situ hybridization (ISH), DNA/RNA extraction, Nanostring-based transcriptional profiling, 
multiplex immunohistochemistry (mIHC) and digital image analysis. The HBC will provide SPORE investigators 
with biospecimens (e.g. serum), derivatives of biospecimens (e.g. unstained slides, DNA,RNA) as well as quality- 
controlled data (e.g. images and image analysis-based data).

## Key facts

- **NIH application ID:** 9986735
- **Project number:** 5P50CA228944-02
- **Recipient organization:** FRED HUTCHINSON CANCER RESEARCH CENTER
- **Principal Investigator:** ROBERT H PIERCE
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $350,195
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9986735

## Citation

> US National Institutes of Health, RePORTER application 9986735, Core 2: Histopathology and Biospecimen Core (5P50CA228944-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9986735. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*