# Core 1: Cellular Microenvironment Engineering

> **NIH NIH U54** · UNIVERSITY OF MINNESOTA · 2020 · $51,509

## Abstract

Abstract
Core 1
The Cell Microenvironment core will provide enabling technologies and develop new methods for controlling
the cellular microenvironment and measuring its effect on cancer cell migration. The primary goals of the core
will be to probe microenvironmental regulators of cell migration to inform mathematical models, probe cell
migration within a physiologically relevant context, and develop highly parallelized platforms for high
throughput studies. Technologies will include, but not be limited to, tools for controlling the mechanical
environment, controlling cell and environment architecture, controlling cell organization within the
microenvironment, controlling chemical gradients, controlling extracellular chemistry, measuring cell migration,
and measuring cell force generation. In addition, tools will be developed for high-throughput cell migration
measurement and high-throughput tissue isolation. The Cell Microenvironment core will support both Project 1
and Project 2 within this center as well as any applicable pilot projects.

## Key facts

- **NIH application ID:** 9987338
- **Project number:** 5U54CA210190-05
- **Recipient organization:** UNIVERSITY OF MINNESOTA
- **Principal Investigator:** David Kevin Wood
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $51,509
- **Award type:** 5
- **Project period:** 2016-08-17 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9987338

## Citation

> US National Institutes of Health, RePORTER application 9987338, Core 1: Cellular Microenvironment Engineering (5U54CA210190-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9987338. Licensed CC0.

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