# Clinical Genome Resource Project

> **NIH NIH U41** · UNIV OF NORTH CAROLINA CHAPEL HILL · 2020 · $1,540,278

## Abstract

Project Summary/Abstract – Clinical Genome Resource Project
ClinGen's critical questions involve determining the clinical validity of gene-disease associations, the
pathogenicity of variants in clinically relevant genes, and the actionability of genomic information.
These questions are addressed in the aims of this section. In addition, since the scope of this project
is to eventually provide curated information about all clinically relevant genes and variants, it is
necessary to establish a strong ecosystem of expert curation groups who have the domain
knowledge to make authoritative assertions. This section will detail the development and expansion of
the Clinical Domain Working Groups and their phenotypic sub-groups for expert curation of genes
and variants.

## Key facts

- **NIH application ID:** 9987673
- **Project number:** 5U41HG009650-04
- **Recipient organization:** UNIV OF NORTH CAROLINA CHAPEL HILL
- **Principal Investigator:** JONATHAN S BERG
- **Activity code:** U41 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,540,278
- **Award type:** 5
- **Project period:** 2017-09-12 → 2021-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9987673

## Citation

> US National Institutes of Health, RePORTER application 9987673, Clinical Genome Resource Project (5U41HG009650-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9987673. Licensed CC0.

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