# Administrative Core and Data Management Center

> **NIH NIH U19** · EMORY UNIVERSITY · 2020 · $1,398,149

## Abstract

The Administrative Core (AC) will be responsible for managing, coordinating, and supervising all TBRU 
activities. The TBRU AC will be directed by a Leadership Team that includes the dual Pis of this application 
(Henry M. Blumberg, MD at Emory and Joel D. Ernst, MD at NYU) and Rafi Ahmed, PhD (Director, Emory 
Vaccine Center) who will serve as TBRU Scientific Advisor. These 3 AC Program Directors (PDs) have 
substantial experience and expertise in immunology, clinical/translational research, and scientific program 
management. They will provide leadership to support scientific investigation into the immunology of latent 
TB infection and facilitate communication among investigators, research projects and cores to ensure there 
is translation and back translation between human subjects studies and animal studies that will utilize a 
non-human primate TB model. The AC includes a Data Management Center (DMC) under the direction of 
Dr. Lance Waller (Chair, Emory Department of Biostatistics and Bioinformatics) that will be responsible for 
collection, storage, quality control, and evaluation of all study data and will provide biostatistical and 
bioinformatics support to TBRU investigators at all of the collaborating sites. The DMC will collaborate with 
the Aeras on the implementation of an integrated data management system for tracking of TBRU specimens 
from both human subjects and non-human primates (NHP) across research projects. The AC will provide 
effective coordination and communication across projects and cores at collaborating institutions; fiscal 
management and regulatory requirement oversight; and as part of evaluation activities will monitor progress 
and assess the degree to which TBRU goals are being met. The PDs will receive input from our Internal 
Advisory Committee and a Steering Committee as well as NIAID and the External Advisory Group; they will 
implement changes based on progress or lack of progress achieved and based on scientific discoveries 
which warrant that new strategies be implemented and new pathways pursued. The AC will also facilitate 
involvement in collaborative research opportunities across the NIAID TBRU network, leveraging our unique 
resources including clinical sites, a NHP model for TB, and investigators with expertise in TB immunology

## Key facts

- **NIH application ID:** 9989024
- **Project number:** 5U19AI111211-07
- **Recipient organization:** EMORY UNIVERSITY
- **Principal Investigator:** HENRY M BLUMBERG
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,398,149
- **Award type:** 5
- **Project period:** 2014-08-11 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9989024

## Citation

> US National Institutes of Health, RePORTER application 9989024, Administrative Core and Data Management Center (5U19AI111211-07). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9989024. Licensed CC0.

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