# Molecular Regulation of Cell Development and Differentiation Phase III COBRE

> **NIH NIH P30** · UNIVERSITY OF KANSAS MEDICAL CENTER · 2020 · $1,117,813

## Abstract

OVERALL PROJECT SUMMARY
ABSTRACT
Funds are requested to renew a Center of Biomedical Research Excellence (COBRE) at the
University of Kansas Medical Center (KUMC) as a Phase III, five year award. This COBRE
has a research focus on the regulation of cell development and differentiation, which may
provide new, therapeutic insights into a host of developmental abnormalities and diseases.
During the initial 10 year term, we will have trained 15 Beginning Investigators and most of
them are becoming successful, independent researchers. An important feature of this
application is the maintenance of 3 scientific Cores that provide research support to all of
the Center faculty as well as to KUMC as a whole. Together with Administrative Core A,
there are Cores supporting transgenesis in mice and rats (Core B), molecular profiling (next
generation sequencing, microarray, and bioinformatics, Core C), and high resolution
imaging (confocal and electron microscopy, Core D). The second major component of this
application is the operation of a Pilot Projects Program in developmental biology, which
represents a natural extension of a pilot program initiated in Phase I and II that has a
proven, successful track record. The outstanding combination of scientific talent, strong
research environment, and substantial institutional commitment to the scientific Cores and
Pilot Projects Program ensure that this COBRE will continue to foster the development of a
thematic, multidisciplinary research effort and enhance the ability of KUMC researchers to
compete for extramural support.

## Key facts

- **NIH application ID:** 9989126
- **Project number:** 5P30GM122731-04
- **Recipient organization:** UNIVERSITY OF KANSAS MEDICAL CENTER
- **Principal Investigator:** DALE R ABRAHAMSON
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,117,813
- **Award type:** 5
- **Project period:** 2017-07-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9989126

## Citation

> US National Institutes of Health, RePORTER application 9989126, Molecular Regulation of Cell Development and Differentiation Phase III COBRE (5P30GM122731-04). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/9989126. Licensed CC0.

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