# Core A: Administrative Core

> **NIH NIH P50** · UT SOUTHWESTERN MEDICAL CENTER · 2020 · $177,643

## Abstract

Project Summary 
This core will provide essential administrative services and support for the UTSW Kidney Cancer SPORE. 
The PI, Dr. Brugarolas, is well-suited to provide overall direction, facilitate interactions, provide scientific 
leadership, and oversee the fiscal management of this complex grant. His scientific background, history of 
participation in many aspects of translational science, and current administrative roles at UTSW (including 
Leader of the Kidney Cancer Program (KCP) and member of the scientific leadership of the NCI-designated, 
now comprehensive, Simmons Cancer Center) make him well-qualified to serve as overall PI and Core 
Director. He is aided by Core A Co-Directors, Dr. Sagalowsky (Professor of Urology and Surgery, and a KCP 
Urology co-Leader), and Dr. McKay (KCP Director of Research Administration), and a first-rate administrative 
team. An Executive Committee (Project Leaders and Core Directors) provides advice for the planning of 
SPORE strategic directions, interactions with departments and administration, faculty recruitment, and 
resource allocation. The KCP and SPORE are well-integrated within the Cancer Center and benefit from many 
shared resources. Institutional commitment is illustrated by (i) participation in the IAB of outstanding 
investigators and institutional leaders, and (ii) a significant financial commitment, including $1,100,000 in 
annual direct support for salaries, benefits and operating costs of key investigators and their laboratories, and 
recurring annual funds of: $150,000 (to match CEP and DRP), $150,000 (to support the Data Analytics Core), 
and $50,000 (discretionary funds). In addition, $1,100,000 in recruitment funds will be made available. The 
SPORE includes a dynamic patient advocacy team of engaged individuals who have participated extensively in 
the KCP, including fundraising, raising awareness, and social events. Our outstanding EAB includes leaders in 
their fields with complementary expertise in clinical/translational research (Arteaga, George, Michaelson, 
Nelson, Oh, Ratain, and Shyr), epidemiological research (Heng and Shyr), and basic research (Simon). The 
Core A aims are straightforward and should fulfill the objective of organizing a complex network of interactions 
involving numerous investigators, staff, cores, and advocates: (1) Oversee and direct all scientific and 
administrative aspects of the SPORE including research/data management, fiscal oversight and adherence, 
and communication aspects: (a) Oversee and maintain scientific quality and rigor of the SPORE; (b) Record, 
monitor, and oversee all budgetary items; (c) Monitor and ensure all aspects of SPORE compliance following 
NCI regulations and requirements, and communicate with NCI Program Officer (and other staff) to ensure 
compliance with reporting; (d) Schedule and organize all meetings, including meetings with the Advisory 
Boards, and Patient Advocates. (2) Oversee and coordinate with the Developmental...

## Key facts

- **NIH application ID:** 9990721
- **Project number:** 5P50CA196516-05
- **Recipient organization:** UT SOUTHWESTERN MEDICAL CENTER
- **Principal Investigator:** James Brugarolas
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $177,643
- **Award type:** 5
- **Project period:** 2016-08-01 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9990721

## Citation

> US National Institutes of Health, RePORTER application 9990721, Core A: Administrative Core (5P50CA196516-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9990721. Licensed CC0.

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