# Human Subjects and Data Integration Core

> **NIH NIH P01** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2020 · $364,562

## Abstract

Project Summary
The Human Subjects and Data Intergration Core will provide a core resource for the recruitment of human
participants for clinical studies of mucus pathology in CF and asthma and for intergrating data from multiple
program sources to facilitate communication and promote the translation plan. Recruiting human subjects for
mechanism-oriented clinical research protocols requires well-developed systems to ensure successful subject
recruitment and the collection of high quality biospecimens from well-characterized human subjects. Dr.
Stephen Lazarus - a highly experienced clinical researcher - currently PI of UCSF AsthmaNet and UCSF
COPD CCRN - will direct the core, which will have two Aims. His Core B team will include personnel with
experience in pulmonary medicine, administration of clinical research, clinical coordination, biostatistics and
data management. The core will have two specific Aims: Aim 1 will recruit and enroll human subjects for
clinical research protocols to support the three tPPG projects. Specifically, to fulfill the clinical aims of Projects
1, 2, and 3, the core will be responsible for recruiting and enrolling participants with asthma, CF, and healthy
controls and in providing support for a Phase 1a study to be performed by a specialist CRO. Aim 2 will develop
and maintain an integrated data management and integration systems for the tPPG. Specifically, Aim 2 will
develop a data integration platform that will enable efficient real-time data sharing across partner institutions
and ensure that physical distances between partner projects and institutions are not a limiting factor in the
success of this tPPG.

## Key facts

- **NIH application ID:** 9990843
- **Project number:** 5P01HL128191-05
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** STEPHEN C LAZARUS
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $364,562
- **Award type:** 5
- **Project period:** 2016-09-01 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9990843

## Citation

> US National Institutes of Health, RePORTER application 9990843, Human Subjects and Data Integration Core (5P01HL128191-05). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9990843. Licensed CC0.

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