# Hopkins Center to Promote resilience in persons and families living with multiple chronic conditions (the PROMOTE Center)

> **NIH NIH P30** · JOHNS HOPKINS UNIVERSITY · 2020 · $498,571

## Abstract

Developing feasible, effective and scalable interventions to improve health among people with multiple chronic
conditions is urgent. However, research gaps hinder intervention development. Most interventions do not
consider co-occurring functional limitations, family caregivers' perspectives or contextual factors that define
social determinants of health. Moreover, interventions commonly focus on deficits rather than strengths. These
limitations are compounded by lack of communication among practitioners and people experiencing multiple
chronic conditions about their goals, values, and preferences. The proposed Hopkins Center to Promote
resilience in persons and families living with multiple chronic conditions (the PROMOTE Center) is poised
to address these gaps. The PROMOTE Center will leverage a unique combination of interdisciplinary expertise
in 1) behavioral intervention research 2) research and statistical methodology and 3) physiological processes
including cytokines found in sweat. Early, mid-career and senior researchers, persons and families experiencing
multiple chronic conditions, and key translational stakeholders will work together to advance the science of
improving health among those with multiple chronic conditions using our innovative ecological resilience
framework. This framework conceptualizes resilience as a life-long process impacted by cumulative interaction
of multiple inter-related factors, such as society, community, and family, individual, physiologic and genomic
factors. The PROMOTE Center will advance science to improve health and care of adults with multiple chronic
conditions by providing expertise, mentorship and resources for the development, implementation and evaluation
of theory-driven interdisciplinary research through three Aims. Aim 1: Establish a community-informed,
sustainable infrastructure with dedicated resources to advance interdisciplinary nursing science that improves
the health of vulnerable adults with multiple chronic conditions and their family caregivers: Aim 2: Foster a new
generation of nursing scholars with skills to lead interdisciplinary research that improves the resilience of adults
with multiple chronic conditions. Aim 3: Leverage unique environmental strengths to enhance dissemination and
translation of evidence-based multiple chronic condition interventions through established partnerships with key
stakeholders. Key innovations of the PROMOTE Center include:
1) Use of Society to Cells Resilience Framework that supports focus on health phases in which people are most
likely to be open to new information and habits; 2) Integration of exploratory aims in pilot studies measuring bio-
markers of resilience with non-invasive sweat measures developed at NINR; and 3) User-centered strengths-
based co-design approaches at each phase of pilot development leading to enhanced participant uptake and
higher likelihood of sustainability and translation to other settings.

## Key facts

- **NIH application ID:** 9990860
- **Project number:** 5P30NR018093-03
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** Sarah L Szanton
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $498,571
- **Award type:** 5
- **Project period:** 2018-08-22 → 2023-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9990860

## Citation

> US National Institutes of Health, RePORTER application 9990860, Hopkins Center to Promote resilience in persons and families living with multiple chronic conditions (the PROMOTE Center) (5P30NR018093-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9990860. Licensed CC0.

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