# 2022 Membrane Transport Proteins GRC/GRS

> **NIH NIH R13** · GORDON RESEARCH CONFERENCES · 2021 · $20,000

## Abstract

PROJECT SUMMARY
The 2020 Gordon Research Conference on Membrane Transporter Proteins titled “Biomedical Transporters:
Physiology, Dysfunction and Targets of Pharmacotherapy” will bring an urgently needed translational focus to
research on clinically relevant and highly druggable membrane transporters. Although they account for 10% of
the human genome and thought contribute to a gamut of highly prevalent (autism, depression, diabetes) as well
as orphan and rare diseases (Christianson syndrome, mucoviscidosis), membrane transporters remain largely
unexplored in their potential as therapeutic targets, and in their association to specific diseases. The impetus in
organizing this conference
is to link genetic, molecular and mechanistic insights on clinically important membrane
transporters, including carriers, ion channels and pumps, to physiological function and disease-related
malfunction. The intent is to offer and discuss opportunities for the development of pharmacotherapies targeting
transporter dysfunctions in disease states. N
ine highly interdisciplinary scientific sessions are bringing together
topics, approaches and novel ideas that are not conventionally related. These range from genetics of transporter
and ion channels in disease states, to unconventional animal models to study transporter, or particular
approaches such as single-molecule fluorescence resonance energy transfer and transcranial magnetic
stimulation. This prevents the perception of a particular approach or topic dominating the conference and
amplifies opportunities for discussion of new ideas. New topics have been introduced (e.g. peptides, hormones,
and neurotransmitter release: the importance of transporters in the gut and brain; invertebrates as animal models
to study transporter functions, etc.) that have never been covered in this conference. Ample discussion time
after each talk, daily posters, and afternoon free time allow for informal discussion, networking and forming new
collaborations. Other special features of the 2020 conference include the Gordon Research Seminar for young
investigators, and the Power Hour for the promotion of women scientists. Notably, we secured Dr. Imogen Coe
as the Discussion Leader of the Power Hour. Dr. Coe is internationally recognized as a Canadian thought leader
in the area of equity, diversity and inclusion (EDI) in science, technology, engineering and math (STEM). She
has advised academia, government and industry on the best practices and approaches to improve EDI in STEM,
particularly in the Canadian post-secondary education (PSE) sector. She has written and spoken about these
issues extensively for platforms such as the Globe and Mail, iPolitics and the CBC. In 2016, she was recognized
as one of Canada's Top 100 Women for her advocacy work promoting equity in STEM. We feel that this
conference will offer plenty of scientific opportunities fostering an environment centered on EDI.

## Key facts

- **NIH application ID:** 9991402
- **Project number:** 1R13NS116946-01
- **Recipient organization:** GORDON RESEARCH CONFERENCES
- **Principal Investigator:** AURELIO GALLI
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $20,000
- **Award type:** 1
- **Project period:** 2021-09-01 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9991402

## Citation

> US National Institutes of Health, RePORTER application 9991402, 2022 Membrane Transport Proteins GRC/GRS (1R13NS116946-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9991402. Licensed CC0.

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