# Genomics

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA AT DAVIS · 2020 · $210,491

## Abstract

PROJECT SUMMARY/ABSTRACT 
The Genomics Shared Resource (GSR) provides comprehensive services and expertise in the area of 
genomics and data analysis and bioinformatics. The GSR provides Cancer Center researchers with direct 
access to the most contemporary genomic applications and state-of-the-art instrumentation for next-generation 
sequencing (NGS), microarray analyses, and NanoString nCounter analyses. This includes Illumina NGS 
systems (MiSeq, HiSeq 2500, 3000, 4000), multi-platform microarray processing equipment for Affymetrix, 
Agilent, and Illumina microarrays, and the required computational hardware and software systems. Together, 
these enable investigators to accomplish virtually every type of application for transcriptomics, genome 
sequencing, epigenomics, and metagenomics, including whole transcriptome analysis, genome-wide profiling 
of single nucleotide variants, copy number analysis, mapping of long-range interactions of DNA regions, and 
molecular characterization of infectious agents. These are generally provided as completely comprehensive, 
sample-to-results services in that investigators need only provide RNA or DNA samples, and the GSR will 
perform all downstream technical processing, as well as data analysis. Ancillary services for DNA/RNA 
isolation, quality assessment, and sample acquisition are also provided. To complement these services and to 
help achieve productive outcomes from genomics experiments, the GSR provides extensive data analysis and 
integrative bioinformatics support, and routinely assists in the preparation of the appropriate sections of 
manuscripts and grant proposals. Additionally, education is an important component of the GSR and is 
provided through training, workshops, and seminars. Unique aspects of the GSR include a strong emphasis on 
facilitating translational science and the custom development of protocols and reagents to address the specific 
goals of investigators' experiments. For translational applications, the GSR has developed and optimized 
protocols enabling the analysis of samples obtained from clinical specimens, such as whole blood, 
serum/plasma, and FFPE specimens. Investigator-driven research often requires protocols and tools to be 
adapted or newly developed. These include modified sequencing library preparations and target enrichment 
panels for mutation screening of tumors and oncogenic viruses. Moreover, the GSR strives to introduce new 
technologies, such as single-cell sequencing and to serve as a pipeline for clinical applications of genomics. 
Taken together, the GSR provides a complete integrative and functional molecular profiling solution to the 
Cancer Center.

## Key facts

- **NIH application ID:** 9993296
- **Project number:** 5P30CA093373-18
- **Recipient organization:** UNIVERSITY OF CALIFORNIA AT DAVIS
- **Principal Investigator:** John D. McPherson
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $210,491
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9993296

## Citation

> US National Institutes of Health, RePORTER application 9993296, Genomics (5P30CA093373-18). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9993296. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*