# Administrative Core

> **NIH NIH U54** · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · 2020 · $279,284

## Abstract

ADMINISTRATIVE CORE – PROJECT SUMMARY 
The overarching framework for this MIT/Mayo PS-OC is to understand the physical interactions between drugs, 
tumor tissue and the microenvironment that influence drug distribution and how potentially heterogeneous drug 
distribution influences tumor cell signaling and therapy resistance emergence (drug efficacy). The PS-OC will 
require a strong administrative unit to support and coordinate Center activities across all sites, projects and 
cores; including day-to-day administrative and financial support, planning and evaluation, ongoing 
communications, pilot and trans-network projects, CAC activities, participation in PS-ON Steering Committee 
and other initiatives developed over the life of the project. The MIT/Mayo PS-OC will be administratively based 
at MIT's Koch Institute of Integrative Cancer Research, an NCI-designated Cancer Center that was established 
in 1974. As demonstrated with past center grants based at the KI, this will allow us to leverage an existing, 
well-organized administrative infrastructure that will provide support for all business aspects related to the 
Center. Primary responsibility for scientific project management and managing the workflow of bio-specimens 
and related high-content data between the two Research Projects and two Shared Resource Cores will be 
based at the Mayo Clinic. Jointly the members of both teams will be referred to as the Administrative Unit (AU).

## Key facts

- **NIH application ID:** 9994237
- **Project number:** 5U54CA210180-05
- **Recipient organization:** MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- **Principal Investigator:** Forest M White
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $279,284
- **Award type:** 5
- **Project period:** 2016-08-29 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9994237

## Citation

> US National Institutes of Health, RePORTER application 9994237, Administrative Core (5U54CA210180-05). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/9994237. Licensed CC0.

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