# 2020 Autophagy in Stress, Development and Disease Gordon Research Conference & Seminar

> **NIH NIH R13** · GORDON RESEARCH CONFERENCES · 2020 · $19,000

## Abstract

PROJECT SUMMARY
This proposal requests partial support for the Gordon Research Conference (GRC) on autophagy to be held
in Ventura Beach, CA, March 8-13, 2019. Autophagy is a fundamental cellular homeostatic mechanism
affecting many developmental processes, as well numerous age-related human diseases such as
neurodegeneration and inflammation. Growing evidence also suggests autophagy as a major molecular
mechanism of aging, warranting its mechanistic study. The broad and long-term goal of this GRC series is
to highlight the expanding role and regulation of autophagy in physiological and pathological processes that
underlie human aging and diseases.
 The specific aims of the 2020 GRC meeting will be to convene 34 invited speakers and discussion
leaders in key areas of autophagy research along with ~200 participants for a five-day conference. The
program will include a keynote session with keynote address from a world leader in inflammation and
non-canonical functions of autophagy genes, a novel molecular aspect of this conference. Other speakers in
the keynote session are the two 2018 GRC chairs who will speak on autophagy and age-related diseases.
The conference will also feature eight sessions that address current issues relating to the regulation and
structure of autophagy proteins, selective mechanisms of autophagy, the role of autophagy in age-related
diseases, along with two additional mechanistic sessions that focus on canonical functions for autophagy
proteins in lysosomal degradation, as well as a session on the new and emerging topic of non-canonical
functions for autophagy proteins. In addition, 16 short talks will be selected from submitted abstracts, and
two poster sessions will permit all participants to contribute to these topics.
 The significance of this application is that the GRC on autophagy has become the cornerstone of the
yearly series of conferences that critically influence, direct and drive research in the international community
of autophagy researchers. GRC meetings bring together a broad group of investigators who are at the
forefront of the autophagy research field, and provide ample opportunities for junior scientists and trainees to
present their work and exchange ideas with leaders in the field, thus nurturing the next generation of
autophagy research leaders, following in the footsteps of the 2016 Nobel Prize winner Dr. Ohsumi, who
discovered the molecular mechanisms of autophagy.
 The health relatedness of this application is that autophagy directly impacts a wide spectrum of human
health and diseases related to aging, such chronic inflammation and neurodegeneration. The research
highlighted by GRC meetings on autophagy will lead to a greater molecular understanding of a critical
process and help develop new approaches to treat age-related diseases and improve healthspan.

## Key facts

- **NIH application ID:** 9994522
- **Project number:** 1R13AG067686-01
- **Recipient organization:** GORDON RESEARCH CONFERENCES
- **Principal Investigator:** Malene Hansen
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $19,000
- **Award type:** 1
- **Project period:** 2020-03-07 → 2023-03-06

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9994522

## Citation

> US National Institutes of Health, RePORTER application 9994522, 2020 Autophagy in Stress, Development and Disease Gordon Research Conference & Seminar (1R13AG067686-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9994522. Licensed CC0.

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