# MRA Melanoma Models Workshop

> **NIH NIH R13** · MELANOMA RESEARCH ALLIANCE FOUNDATION · 2020 · $2,000

## Abstract

Abstract: The Melanoma Models Workshop in Washington, DC, will be organized by the Melanoma Research
Alliance (MRA) and chaired by leading academic and government cancer researchers, and will be held
February 28, 2020. The landscape for melanoma research and treatment has changed dramatically over the
last decade with the approval of new classes of treatments, including immune checkpoint inhibitors and
molecularly targeted therapies. Despite this success, many patients with metastatic melanoma still succumb to
the disease. To continue to advance melanoma research, appropriate model systems are needed that
incorporate and accurately represent melanoma in the context of the new standards of care. The Melanoma
Models Workshop aims to: (1) facilitate an exchange of ideas about how best to leverage and advance
melanoma models to answer fundamental biological questions in melanoma, model patients with melanoma,
and develop new technologies, (2) to increase collaborations between the leading research groups developing
and deploying novel models for melanoma research, and (3) to educate the broader scientific community about
the gaps and opportunities for melanoma research models. Melanoma models include mouse models
(chemically-induced, genetically engineered, syngeneic mouse cell transplant, patient-derived xenograft (PDX)
models), non-mouse animal models (zebrafish, canine) and in vitro models (3D organoids, cell lines).
We have actively ensured gender balance and diversity in the workshop co-chairs, invited speakers and
participants. Importantly, 22 of the confirmed participants hold active funding from the NIH. The proposed
workshop will be attended by trainees; junior and senior principal investigators; and will include leading
scientists that serve on NIH study-sections and/or are members of the MRA Scientific Advisory Panel.
Evaluation of the workshop will include one formative and one summative assessment survey. The formative
assessment survey will be conducted prior to the workshop to solicit participant input into the most pressing
research needs and technical challenges with current models. These data will be analyzed in advance and
presented at the workshop. The summative assessment survey will be conducted following the workshop to
understand what new ideas emerged, what was learned by attendees, what was effective, and what could be
improved for future workshops. The evaluation data will inform dissemination activities and future workshops.
Dissemination activities include submission of a manuscript of workshop proceedings to a cancer research
journal and through a presentation at a national conference. In addition, MRA will prepare a lay summary
report that will be featured in our monthly e-newsletter with a distribution to 12,000 individuals, and that will be
made freely available on the MRA website which has over 55,000 monthly visitors.

## Key facts

- **NIH application ID:** 9994556
- **Project number:** 1R13CA250294-01
- **Recipient organization:** MELANOMA RESEARCH ALLIANCE FOUNDATION
- **Principal Investigator:** MARC S HURLBERT
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $2,000
- **Award type:** 1
- **Project period:** 2020-02-28 → 2021-02-27

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9994556

## Citation

> US National Institutes of Health, RePORTER application 9994556, MRA Melanoma Models Workshop (1R13CA250294-01). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9994556. Licensed CC0.

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