# Sample Processing and Immune Assessment

> **NIH NIH P01** · DANA-FARBER CANCER INST · 2020 · $324,407

## Abstract

Project Summary
The purpose of Core 2 is to provide a centralized laboratory resource for processing, cryopreserving and
distributing patient samples and to monitor the kinetics of immune reconstitution following allogeneic
hematopoietic stem cell transplantation (HCT). Prior to transplantation, peripheral blood mononuclear cells
(PBMC), bone marrow and serum or plasma are obtained from all patients enrolled on clinical trials supported
by this Program Project. PBMC, plasma and serum are also obtained from normal stem cell donors. Following
HCT, additional samples are obtained at regular intervals. All of these samples are processed, cryopreserved,
entered into a computerized inventory and made available to Program investigators. Patient confidentiality is
maintained at all levels and samples are only be obtained from patients who have provided informed consent.
To support clinical trials and laboratory studies in each project, Core 2 also provides a series of phenotypic and
functional immune assays that are used to monitor the effects of different immunologic interventions. Results of
each of these assays are provided to Dr. Kim (Biostatistics – Core 1) for correlation with laboratory studies in
each project as well as with clinical outcomes.

## Key facts

- **NIH application ID:** 9995452
- **Project number:** 5P01CA229092-02
- **Recipient organization:** DANA-FARBER CANCER INST
- **Principal Investigator:** JEROME RITZ
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $324,407
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9995452

## Citation

> US National Institutes of Health, RePORTER application 9995452, Sample Processing and Immune Assessment (5P01CA229092-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9995452. Licensed CC0.

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