# Sample Processing and Immunoassay Research

> **NIH NIH P30** · JOHNS HOPKINS UNIVERSITY · 2020 · $221,498

## Abstract

PROJECT SUMMARY
 The Sample Processing and Immunoassay REsearch SPIRE Core (Core C) is designed to
serve the RDRCC research community as a centralized resource for preparation and storage of
clinically derived samples, for conducting a range of standard and innovative assays on clinically
derived material and for serving as a conduit to other relevant research cores within the Institution.
This core has facilitated, through disease-specific centers of excellence, the generation of large
specimen bio-repositories recovered from well-pedigreed patient cohorts. In this manner, this well-
established core, by providing biospecimen acquisition, processing, storage and retrieval services,
has become a critical partner in enabling discovery at the translational interface, and in attracting the
interest of a growing group of researchers. In addition, the high-quality assay services provided by
Core C have resulted in numerous peer-reviewed publications, abstracts and investigator-initiated
grant proposals. The assay capabilities in the Core play a critical role in pathway validation in human
rheumatic disease cohorts. The aims of this proposal are to sustain, grow and evolve this vital
resource. We propose to expand the range of services offered to include innovative, cutting-edge
technologies/approaches and serve as consultants and the pipeline to the necessary institutional
expertise and resources that provide NextGen analytical approaches, and for advanced data analysis
and interpretation. This interactive, dynamic framework has, and will continue to catalyze major leaps
forward in research on the autoimmune rheumatic diseases.
 Core C will be directed by Drs. Casciola-Rosen and Soloski, both of whom have many years of
experience in immunology, assay development, and directing high quality research responsive Cores.
Drs. Andrade and Gutierrez, both of whom have many years of experience working with this Core
team, will provide additional leadership. The close collaboration of this Core with the Administrative
(Core A), Research Management and Patient Integrated Data (RAPID, Core B) and Data Science
(Core D) Cores provides a powerful matrix to maximize synergies, resources and innovative
collaborations in the environment.

## Key facts

- **NIH application ID:** 9996492
- **Project number:** 5P30AR070254-05
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** LIVIA A CASCIOLA-ROSEN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $221,498
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9996492

## Citation

> US National Institutes of Health, RePORTER application 9996492, Sample Processing and Immunoassay Research (5P30AR070254-05). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9996492. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*