# Shared Resource: Biostatistics and Bioinformatics Facility

> **NIH NIH P30** · RESEARCH INST OF FOX CHASE CAN CTR · 2020 · $327,120

## Abstract

COMPUTATIONAL/INFORMATICS SHARED RESOURCE: BIOSTATISTICS AND BIOINFORMATICS
FACILITY (BBF)
PROJECT SUMMARY/ABSTRACT
BBF was rated "Outstanding" at the last review. The Biostatistics and Bioinformatics Facility (BBF) is a shared,
institutional resource for biostatistics and bioinformatics collaboration and related methodological research.
BBF is recognized Center-wide as a critical component of the research infrastructure and serves Cancer
Center members from all five Research Programs. The BBF, with the direction of Eric Ross, PhD and a staff
of 7 FTEs, provides Cancer Center members with rigorous biostatistics and bioinformatics design, analysis and
interpretation of experiments and studies. Facility staff are broadly skilled in quantitative and computational
methods for clinical trials, pre-clinical studies, biological experiments, translational investigations and cancer
prevention and control problems. Its members embrace new problems and technologies that surface in a
rapidly changing scientific environment. Facility biostatisticians play essential roles in all phases of study
planning, reporting and design including sample size determination, randomization, and interim and final
analyses. Bioinformaticians provide expertise for the analysis and exploration of diverse laboratory results
including high throughput data. All Cancer Center members have ready access to the BBF’s coordinated and
cost effective biostatistics and bioinformatics services. BBF maintains statistical and bioinformatics software
packages for data analysis; visualization; sample size/power estimation; sequence analysis; pathway and
network analysis; and annotation. BBF interactions with laboratory, cancer control, translational and clinical
investigators have extended the interpretation of experimental data and contributed substantially to FCCC
research. BBF’s members published 260 papers from 2011 to June 2015 (91% increase over 2006-June
2010). BBF members’ development of specialized biostatistics and bioinformatics methods to support Cancer
Center projects resulted in 16 methodology/first author publications in clinical trial design, observational study
methods and high throughput data analyses. From 2011-2014, BBF provided 39,359 hours of support to the
research activities of 105 Cancer Center members. 32,565 hours were in support of peer-review-funded
members from all five Research Programs. In 2014, the facility provided 9,534 consulting hours supporting 90
Cancer Center members. 7,423 hours were in support of 67 peer-reviewed members. BBF reviews the
statistical soundness of all protocols involving human subjects in conjunction with the Research Review
Committee. It is advised by a Facility Advisory Committee (FAC) that meets at least annually.
Recommendations from the FAC are directed to a governing Facility Parent Oversight Committee (FPOC) that
serves to ensure that the BBF continues to have the resources needed to provide the highest quality of
quantitative serv...

## Key facts

- **NIH application ID:** 9996568
- **Project number:** 5P30CA006927-55
- **Recipient organization:** RESEARCH INST OF FOX CHASE CAN CTR
- **Principal Investigator:** Eric Andrew Ross
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $327,120
- **Award type:** 5
- **Project period:** 1997-07-01 → 2024-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9996568

## Citation

> US National Institutes of Health, RePORTER application 9996568, Shared Resource: Biostatistics and Bioinformatics Facility (5P30CA006927-55). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9996568. Licensed CC0.

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