# Behavioral Science and Biostatistics Resource Core for Alcohol-HIV Research

> **NIH NIH U24** · BROWN UNIVERSITY · 2020 · $626,693

## Abstract

Project Summary/Abstract
This application is a renewal of U24 AA022003 (PI, Kahler), a resource core that has been coding mechanisms
of behavior change in alcohol-HIV interventions conducted by the Brown University Alcohol Research Center
on HIV (ARCH) and Yale University. In this renewal, the core has been expanded to incorporate a broader
range of functions and to support work being done in the Southern HIV & Alcohol Research Consortium
(SHARC) and work conducted in collaboration between the Brown ARCH and SHARC. Specifically, this
Behavioral Science and Biostatistics Resource Core (BSBRC) will support state-of-the-art methods for
understanding the role that alcohol has on health outcomes in people living with HIV (PLWH) and for
implementing and understanding effective interventions to reduce drinking, enhance engagement in HIV care,
and reduce sexual risk behaviors in PLWH. Towards these ends, the BSBRC will bring together expertise in (a)
the effective implementation of contingency management (CM) and motivational interventions (MI) to reduce
drinking and improve related HIV outcomes, (b) the study of mechanisms of behavior change in alcohol
counseling and HIV care, and (c) the use of sophisticated data analytic methods for observational and
experimental data. This multidisciplinary team of experts will share intellectual resources and conduct work
across geographically and racially/ethnically diverse populations to forward science on how best to address
excessive alcohol use, a key contributor to HIV transmission, morbidity, and mortality in PLWH. Specific
objectives of the core include: (1) to provide expertise in Contingency Management procedures and in the use
of the SCRAM Continuous Alcohol Monitor biosensor, (2) to train and supervise staff on the implementation of
an evidence-based MI to reduce alcohol use using high definition videoconferencing; (3) to conduct state-of-
the-art, clinically relevant research on mechanisms of behavior change in alcohol interventions among PLWH
including examination of the effects that videoconferencing and CM have on the therapeutic processes
hypothesized in MI change theory; (4) to provide data management and biostatistical leadership and support to
the SHARC U01 and, when resources permit, to other CHAART consortia. The core will contribute to the
overall success of the SHARC and ARCH projects it supports while also forwarding science in intervention and
statistical methodology with a particular focus on the intersection between alcohol and HIV. Thus, this resource
core can make a substantial impact in reducing the burden of disease associated with excessive drinking and
HIV.

## Key facts

- **NIH application ID:** 9997766
- **Project number:** 5U24AA022003-09
- **Recipient organization:** BROWN UNIVERSITY
- **Principal Investigator:** Christopher W. Kahler
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $626,693
- **Award type:** 5
- **Project period:** 2012-09-20 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9997766

## Citation

> US National Institutes of Health, RePORTER application 9997766, Behavioral Science and Biostatistics Resource Core for Alcohol-HIV Research (5U24AA022003-09). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9997766. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*