# Core A: Biospecimen Repository

> **NIH NIH P50** · SLOAN-KETTERING INST CAN RESEARCH · 2020 · $220,594

## Abstract

The Biospecimen Repository Core is designed to provide support to the basic translational research efforts of
the SPORE. The Core will continue to play a central role in collecting, annotating, storing, distributing, and
tracking prostate cancer tissue and blood biospecimens from patients enrolled in research protocols. Detailed
biospecimen annotation, including documentation of pre-analytic processing variables, pathology findings, and
patient clinical history information will be recorded in robust relational databases. We will conduct rigorous data
quality assurance and quality control measures, and standardized longitudinal follow-up of all consented
patients with materials in the prostate biospecimen repository. The Core will provide SPORE investigators with
expert histopathological evaluation of tumor samples both from patients enrolled on research protocols and
from xenograft models. The Core will also provide assistance in performing and interpreting
immunohistochemical and in situ hybridization assays, in selecting tissue for microdissection and construction
of arrays, and in collaborating with project leaders and the Biostatistics and Bioinformatics Cores.
Specific Aim 1. To maintain and expand a model prostate cancer resource to collect, annotate, store, and
distribute biospecimens for translational prostate cancer research
Specific Aim 2. To perform systematic pathologic evaluation of all human and animal tissue samples and
preparation of appropriate tissues for use by SPORE investigators
Specific Aim 3. To collect, process, annotate, store, and distribute blood specimens under Clinical Laboratory
Improvement Amendments (CLIA)-regulatory conditions for use by SPORE investigators

## Key facts

- **NIH application ID:** 9998850
- **Project number:** 5P50CA092629-20
- **Recipient organization:** SLOAN-KETTERING INST CAN RESEARCH
- **Principal Investigator:** Victor Reuter
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $220,594
- **Award type:** 5
- **Project period:** 2001-09-14 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9998850

## Citation

> US National Institutes of Health, RePORTER application 9998850, Core A: Biospecimen Repository (5P50CA092629-20). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9998850. Licensed CC0.

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