# Analytical Imaging

> **NIH NIH P30** · ALBERT EINSTEIN COLLEGE OF MEDICINE · 2020 · $167,401

## Abstract

PROJECT SUMMARY – ANALYTICAL IMAGING FACILITY SHARED RESOURCE
The Analytical Imaging Facility (AIF) is a comprehensive microscopy shared resource that offers a broad
spectrum of imaging technologies to AECC investigators. These include: macro-imaging with a stereoscope,
classical microscopy including brightfield, darkfield, phase contrast, Nomarski differential interference contrast
and wide-field epifluorescence, confocal microscopy for cell culture and tissues, high-speed and high-capacity
automatic slide scanning, high speed spinning disk confocal microscopy for live cells, intravital multiphoton
microscopy for live animals, super-resolution STORM and SIM microscopy, standard transmission and
scanning electron microscopy (TEM & SEM), cryoEM of macromolecules, electron tomography and 3D
reconstruction of high pressure frozen cells and tissue, automated imaging of serial sections by field emission
SEM (FESEM) and SEM of frozen hydrated cells and tissues. The wide range of imaging modalities is
especially important for studying the diverse biological models utilized by the AECC research community. For
instance, cells labeled with fluorescent reporter genes may be imaged at the whole animal or whole organ level
down to subcellular and molecular levels. Over the span of 23 years, the AIF has expanded its dedicated
laboratory space and staff, and added multiple new instruments and equipment upgrades. This growth has
been enabled by funding from Cancer Center and College and Shared Instruments Grants. This facility
furnishes AECC investigators with the majority of their on-site access to routine and sophisticated imaging
technologies. The technologies provided are essential to the research of many AECC members, and cannot be
outsourced or obtained at other sites in any practical or cost effective way. Having the technology and staff in
one location provides continuity, facilitates cross-training and adds value to the AECC researchers who use
microscopy. Beyond making routine and complex imaging technologies available to the AECC community, the
AIF also provides comprehensive training in most technologies so that AECC members and their staff are
competent in the operations of the equipment, image analysis and the interpretation of the data acquired. This
is accomplished by supporting routine as well as advanced microscopy applications, training users in
microscopy and image analysis software, hosting regular workshops on microscopy and image processing and
introducing innovative imaging technologies developed at this center to meet the needs of AECC investigators.

## Key facts

- **NIH application ID:** 9998868
- **Project number:** 5P30CA013330-48
- **Recipient organization:** ALBERT EINSTEIN COLLEGE OF MEDICINE
- **Principal Investigator:** JOHN S CONDEELIS
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $167,401
- **Award type:** 5
- **Project period:** 1997-06-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9998868

## Citation

> US National Institutes of Health, RePORTER application 9998868, Analytical Imaging (5P30CA013330-48). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9998868. Licensed CC0.

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