# Cancer Pharmacokinetics Research Specialist

> **NIH NIH R50** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2020 · $181,103

## Abstract

Summary
 The long-term goal of this application is to provide stable research funding for a Cancer Pharmacokinetics
Research Specialist within the University of Pittsburgh Cancer Institute (UPCI) Cancer Pharmacokinetics and
Pharmacodynamics Facility (CPPF).
 The activities of the Cancer Pharmacokinetics Research Specialist can be categorized broadly into: (1)
Pharmacokinetic assay development and validation; (2) Preclinical pharmacokinetics; and (3) Clinical
pharmacokinetics. The Cancer Pharmacokinetics Research Specialist plays an absolutely critical role in
developing and validating novel LC-MS/MS methodologies, and applying them to precisely delineate the PK
and metabolism of novel and established agents.
 The stated new research directions of: (1) generic assay platform development; (2) metabolite structural
elucidation by high-resolution mass spectrometer; and (3) population-pharmacokinetic analyses of clinical
pharmacokinetic data, are relevant and sure to enhance the research output of the CPPF. This award will allow
the CPPF Cancer Pharmacokinetics Research Specialist to continue to be at the cutting edge, with the ultimate
aim of serving the scientific community in early drug development needs.

## Key facts

- **NIH application ID:** 9999469
- **Project number:** 5R50CA211241-05
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **Principal Investigator:** Robert Parise
- **Activity code:** R50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $181,103
- **Award type:** 5
- **Project period:** 2016-09-15 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9999469

## Citation

> US National Institutes of Health, RePORTER application 9999469, Cancer Pharmacokinetics Research Specialist (5R50CA211241-05). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9999469. Licensed CC0.

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