# Evidence for Value-based Prescription Drug Plan for Diabetes, CVD and Chronic Illness

> **NIH NIH R01** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2020 · $431,384

## Abstract

Project Summary/Abstract
 Value-based insurance design (VBID) is widely viewed as an important tool to improve the health of
consumers and the efficiency of health care spending in the U.S. VBID has found its widest applicability with
respect to prescription drugs, and the potential of VBID may be greatest for elderly persons with chronic
illnesses such as diabetes and cardiovascular disease that are effectively treated with prescription drugs. The
essential feature of a VBID is the fact that prescription drugs may be substitutes or complements with other
healthcare services. Therefore, changes in the use of prescription drugs, for example, because of changes in
cost sharing, may affect health and alter use of other healthcare services. While conceptually appealing, the
evidence to support VBID is lacking. Specifically, an effective VBID requires knowledge of the following: the
effect of cost sharing on prescription drugs on the use of prescription drugs; the effect of cost sharing on
prescription drugs on use of other healthcare services; and the effect of cost sharing on prescription drugs on
health. While some evidence related to each of these links in the causal chain exists, it is not sufficiently
detailed to design an effective “value-based” prescription drug benefit plan. Our proposed research will provide
evidence that will fill in much of the existing knowledge gaps and be instrumental in advancing the scientific
base of evidence to inform future VBID, for example, as envisioned in the “Model Test” program initiated by
CMS.
 The proposed research will exploit the large and widespread changes over time in consumer cost-sharing
within Medicare Part D plans to estimate the causal association between cost sharing and use of prescription
drugs among the elderly, particularly among those with chronic illnesses such as diabetes and cardiovascular
disease. We will then exploit the changes in consumer cost sharing to estimate the causal association between
cost sharing and use of health care services other than prescription drugs, and cost sharing and health. These
aims directly address the specific hypotheses described in PA-17-088: “Differences in health outcomes
between alternative treatment regimens or health care management strategies for older patients with specific
common conditions in old age, or with specific combinations of two or more chronic conditions.” The research
also focuses on the target population of PA-17-088: “Groups identified by disease or non-disease status for
comparison analyses (e.g., hip fracture patients) either retrospectively for risk factors (e.g., case-control
studies) or prospectively for health-related outcomes. Groups defined by administrative databases to explore
specific hypotheses regarding aging changes across the lifespan or diagnosis and management of medical
conditions common among the elderly (e.g., CMS data, managed and/or accountable care organization data,
health insurance databases, electronic healt...

## Key facts

- **NIH application ID:** 9999996
- **Project number:** 5R01AG059234-02
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** GEOFFREY F JOYCE
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $431,384
- **Award type:** 5
- **Project period:** 2019-09-01 → 2022-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9999996

## Citation

> US National Institutes of Health, RePORTER application 9999996, Evidence for Value-based Prescription Drug Plan for Diabetes, CVD and Chronic Illness (5R01AG059234-02). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9999996. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*
