Collaborative Research: RESEARCH-PGR: A Genome-Wide Approach to Characterize Evolutionarily Conserved Plant Signaling Modules that Underlie Organ Development

NSF Award Search · 01002526DB NSF RESEARCH & RELATED ACTIVIT · $1,503,250 · view on nsf.gov ↗

Abstract

Plants comprise 80% of the total biomass on the planet and 50-90% of the human diet. Thus, understanding how plants grow and develop is critical for the success of the human population. As in all multicellular organisms, plant cells must communicate with each other to form boundaries between tissues and ultimately establish a body plan. Unlike animal cells, plant cells are surrounded by walls permanently locking cells to their sisters. The cell wall not only establishes boundaries between single cells but also dictates that organ development results from cell expansion that must be coordinated with neighboring cells in the organ. This proposal will investigate how small molecules made by the plant orchestrate organ formation. This project will also contribute to the public’s understanding of plant biology and inspire the next generation of scientists. A teaching program will be launched in rural high schools centered around active learning activities that will enhance student’s knowledge of agriculture and plant science. An annual public science fair will highlight how microscopy propels scientific discovery. Sulfated peptides are a subset of plant peptide hormones involved in regulation of organ formation. These peptides are recognized by plasma membrane-bound receptor-like kinases that contain an extracellular leucine-rich repeat. While many of the peptides and receptors are conserved, it has been challenging to narrow down peptide-receptor pairs and their functions due

Key facts

NSF award ID
2436798
Awardee
Dartmouth College (NH)
SAM.gov UEI
EB8ASJBCFER9
PI
Magdalena Bezanilla
Primary program
01002526DB NSF RESEARCH & RELATED ACTIVIT
All programs
PLANT GENOME RESEARCH RESOURCE, PLANT GENOME RESEARCH PROJECT, INTELLIGENT CONTROL INITIATIVE, Biotechnology, GRADUATE INVOLVEMENT, AGRICULTURAL BIOTECHNOLOGY, EXP PROG TO STIM COMP RES
Estimated total
$1,503,250
Funds obligated
$850,435
Transaction type
Continuing Grant
Period
06/01/2025 → 05/31/2030