CAREER: Leveraging Early Oxophilic Transition Metals for Organic Synthesis

NSF Award Search · 01002526DB NSF RESEARCH & RELATED ACTIVIT · $660,262 · view on nsf.gov ↗

Abstract

With the support of the Chemical Synthesis Program in the Division of Chemistry, Professor Liela Romero of Baylor University is developing new strategies for chemical synthesis using early transition metal catalysts. The unique properties of these metal complexes are selectively transforming oxygen-containing molecules into valuable chemical building blocks through uncommon, highly selective interconversions. These activities are improving synthetic efficiency with applications across various industries. This program is also providing graduate students with training in synthetic chemistry and catalysis, while also creating new opportunities to incorporate concepts of catalysis into undergraduate curriculum. Further, Professor Romero is working to increase participation in hands-on chemical education through (1) organizing an instrumentation workshop for students and faculty at small colleges and universities in the region, and (2) developing and sharing educational resources to help educators better support students within the chemistry community. While decades of literature on zirconium hydrides have established their usefulness in organic synthesis, much of this work is stoichiometric in metal and carried out through multi-stage processes. Moreover, access to these complexes using conventional methods can require the use of aggressive reductants or harsh conditions. The Romero group is developing new strategies to generate and turnover zirconium hydride catalysts for red

Key facts

NSF award ID
2440697
Awardee
Baylor University (TX)
SAM.gov UEI
C6T9BYG5EYX5
PI
Liela Romero
Primary program
01002526DB NSF RESEARCH & RELATED ACTIVIT
All programs
Advanced Manufacturing, CAREER-Faculty Erly Career Dev
Estimated total
$660,262
Funds obligated
$509,210
Transaction type
Continuing Grant
Period
06/01/2025 → 05/31/2030