CAREER: Experimental evaluation of dispersal as a parasite avoidance strategy

NSF Award Search · 01002526DB NSF RESEARCH & RELATED ACTIVIT · $1,500,000 · view on nsf.gov ↗

Abstract

Infectious diseases are widespread and reduce the health of their hosts. Hosts thus experience strong selection to avoid contracting an infection. This research will advance our understanding of the evolution of host strategies to avoid contact with parasites. Researchers for this project propose that hosts avoid their parasites through dispersal, the permanent movement between sites. This idea is important because it asserts that dispersal, a widespread behavior, drives rates of contact with parasites and evolves as part of hosts’ defense against infection. The proposed work will use experiments and field surveys to test parasites as drivers of dispersal evolution. The project will also create educational programs that engage community college transfer students in scientific research. The main idea of this work is that dispersal strategies evolve to be sensitive to infection risk. The researchers predict that hosts evolve to disperse early in an epidemic, when infection risk is low. The work will conduct experiments with a free-living nematode and its natural parasites. The researchers will track the evolution of dispersal strategies under parasite selection and identify the genetics and mechanisms of adaptation. They will also test if dispersal limits selection for other defenses. Finally, they will assess whether dispersal reduces infection risk in the wild, by observing the natural distribution of parasites. Community college students will contribute to this work thro

Key facts

NSF award ID
2441427
Awardee
University of Virginia Main Campus (VA)
SAM.gov UEI
JJG6HU8PA4S5
PI
Amanda K Gibson
Primary program
01002526DB NSF RESEARCH & RELATED ACTIVIT
All programs
CAREER-Faculty Erly Career Dev
Estimated total
$1,500,000
Funds obligated
$1,500,000
Transaction type
Standard Grant
Period
09/01/2025 → 08/31/2030