This Research Experience for Undergraduates (REU) Site at the University of Mississippi, located in Oxford, MS, supports the training of 10 students for 10 weeks during the summers of 2025-2027. The site will offer original research projects in experimental and theoretical physical chemistry. These research projects foster communication and collaboration between members of physical and computational chemistry groups, which increases literacy in high performance computing and its applicability to chemistry. In addition to participating in research, students will develop a deeper knowledge in physical chemistry through faculty-led lectures on topics like quantum chemistry, molecular spectroscopy, physical organic and biophysical chemistry. Students will also engage in a summer-long schedule of organized professional development and social activities with University of Mississippi undergraduate and graduate students, faculty and staff. These activities are expected to prepare students for chemistry careers and help to build a network of peers and faculty. To broaden participation and develop an effective chemistry workforce, this site will recruit students from throughout the U.S., particularly those from institutions with limited research opportunities. Student participants will perform original research in the laboratories of faculty members and using the Mississippi Center for Supercomputing Research (MCSR). Centered around experimental and theoretical physical chemistry,