Biological invasions by non-native species can harm local economies, food security, and human health and well-being and are inherently a multi-national phenomenon. Recent estimates of global annual costs of invasive species exceed $400 billion USD, including substantial impacts on people’s livelihoods and quality of life. Non-native species continue to spread rapidly in all biomes – on land, in freshwater, and in our oceans. Information about the extent of current invasions in our oceans, however, is limited, creating gaps in knowledge that weaken biosecurity efforts aimed at the prevention and management of invasive species. Clear communication pathways for consolidating information on known marine invasions across international stakeholders, and widely adopted standardized protocols for detecting new or undocumented invasions, are needed to tackle this grand challenge and minimize impacts on society. Harnessing complementary expertise across highly invested regional and global networks, the AccelNet BRIDGE program will advance key fundamental science at scales needed to support and inform effective biosecurity policy and contribute to training a skilled US-based workforce, poised to leverage international team science to engage with this challenge. These efforts will make detection of marine invasions more efficient, robust, integrated, and informative across global economies, which is essential for the prevention of future invasions. The AccelNet BRIDGE program will p