# Oxidant-Controlled Decarboxylation Reactions

> **NSF 01002526DB NSF RESEARCH & RELATED ACTIVIT** · University of Minnesota-Twin Cities (MN) · $570,000

## Abstract

With the support of the Chemical Catalysis Program of the Division of Chemistry, Professor Hoover of the Department of Chemistry at the University of Minnesota-Twin Cities is studying new catalysts to convert carboxylic acids to value-added compounds. Current routes to synthesize molecules used in medicine, agriculture and materials applications rely on expensive starting materials and involve lengthy multi-step syntheses. In contrast, carboxylic acids are abundant starting materials that can be obtained from renewable sources. The development of new catalysts to utilize these precursors will improve the efficiency and sustainability of these processes by reducing the number of synthetic steps required and minimizing the formation of waste byproducts. The broader impacts of the project will extend to current and future high school teachers who will participate in summer research opportunities with the Hoover lab. This program will promote careers in science and engineering and aid in developing the STEM workforce by encouraging and enabling research participation by Minnesota’s current and future teachers.

This project will establish two new classes of oxidant-controlled reactions of carboxylic acids. Although oxidative decarboxylation reactions are an attractive approach to generate a variety of value-added targets from simple and abundant precursors, there are limited examples of such reactions that operate with high efficiency and selectivity. The approach will leverage

## Key facts

- **NSF award ID:** 2452506
- **Awardee organization:** University of Minnesota-Twin Cities (MN)
- **SAM.gov UEI:** KABJZBBJ4B54
- **PI:** Jessica M Hoover
- **Primary program:** 01002526DB NSF RESEARCH & RELATED ACTIVIT
- **All programs:** —
- **Estimated total:** $570,000
- **Funds obligated:** $570,000
- **Transaction type:** Standard Grant
- **Period:** 09/01/2025 → 08/31/2028

## Primary source

NSF Award Search: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2452506

## Citation

> US National Science Foundation, Award 2452506, Oxidant-Controlled Decarboxylation Reactions. Retrieved via AI Analytics 2026-06-06 from https://api.ai-analytics.org/grant/nsf/2452506. Licensed CC0.

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