# Collaborative Research: Sequence-Driven Assembly in Polyelectrolyte/Surfactant Complex Coacervates

> **NSF 01002526DB NSF RESEARCH & RELATED ACTIVIT** · University of Illinois at Urbana-Champaign (IL) · $500,413

## Abstract

Non-technical Abstract

Molecules can arrange to form larger structures, a process that is key to both complex living tissues and new, advanced materials. For example, scientists have long studied how specific sequences of amino acids fold to create proteins that act as tiny machines. Similarly, surfactants (e.g., the molecules in soap) can assemble into spheres, layers, and tubes. In both cases, the assembled structure is important for their practical use. For example, long, tube-shaped surfactant structures help to thicken shampoos while also cleaning hair. However, the ability to form this tube-like structure is usually related to shape of the surfactant molecule itself. This project seeks to learn from the ways in which long, charged molecules with protein-like sequences attract oppositely-charged surfactants, and form materials with desired structures. This effort uses both experiments and computation and will benefit society and the U.S. by establishing a versatile class of biology-inspired materials for use across chemical, agricultural, and industrial applications. The research will also involve the interdisciplinary training of researchers with broad expertise in chemistry, engineering, and physics, via both student mentorship and engagement with K-12 students.

Technical Abstract

This project will establish how sequence-controlled polymers can be used for the rational design of surfactant-containing materials. This effort will leverage sequence-defined polype

## Key facts

- **NSF award ID:** 2452572
- **Awardee organization:** University of Illinois at Urbana-Champaign (IL)
- **SAM.gov UEI:** Y8CWNJRCNN91
- **PI:** Charles E Sing
- **Primary program:** 01002526DB NSF RESEARCH & RELATED ACTIVIT
- **All programs:** BIO-RELATED MATERIALS RESEARCH
- **Estimated total:** $500,413
- **Funds obligated:** $263,403
- **Transaction type:** Continuing Grant
- **Period:** 09/01/2025 → 08/31/2029

## Primary source

NSF Award Search: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2452572

## Citation

> US National Science Foundation, Award 2452572, Collaborative Research: Sequence-Driven Assembly in Polyelectrolyte/Surfactant Complex Coacervates. Retrieved via AI Analytics 2026-06-07 from https://api.ai-analytics.org/grant/nsf/2452572. Licensed CC0.

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