The Historically Black Colleges and Universities Undergraduate Program (HBCU-UP) through Targeted Infusion Projects supports the development, implementation, and study of evidence-based, innovative models and approaches for improving the preparation and success of undergraduate students enrolled at HBCUs so that they may pursue science, technology, engineering, or mathematics (STEM) graduate programs and/or careers. This project contributes to HBCU-UP program goals by transforming the way chemistry is taught and learned. Through the creation and study of immersive virtual reality learning environments, the research team provides an opportunity for students to better visualize and understand complex chemistry concepts. Specific project goals include the development and implementation of updated curriculum materials, virtual reality labs, and professional development workshops for chemistry instruction. The project addresses a national need to improve student engagement and achievement in science, especially among students in the rural south. Outreach activities allow the project to engage high school and community college students in science education innovations to increase awareness of and interest in chemistry. By developing interactive tools and faculty training grounded in educational and psychological principles, the project supports the advancement of science, fosters innovation in teaching, and contributes to workforce development in fields critical to regional and nat