The Strong Nuclear Force, one of the four fundamental forces in the universe, is being studied at particle collider facilities around the world, such as the Large Hadron Collider (LHC) at the European Center for Nuclear Research (CERN), the Relativistic Heavy-Ion Collider (RHIC) at Brookhaven National Laboratory (BNL), and the planned Electron Ion Collider (EIC) at BNL. In these facilities, protons, nuclei, or electrons collide at high energies to investigate the structure of protons and the behavior of nuclear matter in extreme conditions. A full theoretical understanding of the Strong Force, by solving Quantum Chromodynamics (QCD), has still not been achieved. To connect such theoretical calculations to experimental data from collider facilities, large scale computer simulations are needed. Utilizing advanced statistical methods, it is then possible to extract fundamental properties of QCD from data. This team, a multi-disciplinary collaboration of physicists, computer scientists, and statisticians, is developing a software framework, the Comprehensive Event Generator for Chromodynamics with a Statistically and Computationally Advanced Program Envelope (C-SCAPE), to bridge theory and experiment. As a software framework, C-SCAPE utilizes a strategy of breaking complicated processes into subprocesses with their own simulation codes, or modules, that can work together seamlessly. C-SCAPE builds on the success of previous frameworks with more limited capabilities. C-SCAPE can s