Laplace approximation in survival data analysis

NSF Award Search · 01002526DB NSF RESEARCH & RELATED ACTIVIT · $119,952 · view on nsf.gov ↗

Abstract

Survival data analysis is a vital area of statistics that helps researchers understand outcomes such as time to disease onset, recovery after treatment, or mortality. This type of analysis provides health professionals with insights into how various factors, such as treatments or risk exposures, affect patient outcomes over time. However, current methods for analyzing survival data using semiparametric linear models often face limitations: they either involve significant computational challenges or rely on inaccurate approximations. This project addresses these gaps by developing new and more accurate statistical methodologies that are also computationally efficient. These tools will improve our ability to assess the impact of clinical and environmental factors on survival, ultimately supporting better disease prevention and treatment strategies. In doing so, the research promotes national health, enhances healthcare effectiveness, and contributes to overall societal well-being. Beyond its technical contributions, the project delivers broad societal benefits through its strong commitment to education, collaboration, and open science. The investigators will mentor graduate students and create new interdisciplinary coursework at the intersection of statistics and medicine. All developed software tools will be made openly available to encourage reproducibility and accessibility in scientific research. By fostering collaboration across statistics, medicine, and computer science,

Key facts

NSF award ID
2515361
Awardee
Georgia Southern University Research and Service Foundation, Inc (GA)
SAM.gov UEI
FL4AUYLFP7E8
PI
Lili Yu
Primary program
01002526DB NSF RESEARCH & RELATED ACTIVIT
All programs
Biotechnology
Estimated total
$119,952
Funds obligated
$119,952
Transaction type
Standard Grant
Period
08/15/2025 → 07/31/2028