# Collaborative Research: eMB: Math-model Informed Neural Network (MINN) based on Emerging Mathematics in Mosquito-Dengue Biology

> **NSF 01002526DB NSF RESEARCH & RELATED ACTIVIT** · San Diego State University Foundation (CA) · $200,000

## Abstract

Currently, about half of the world’s population, about 4 billion people, live in areas with a risk of dengue infection, with further increased public health concerns due to recent evolutionary adaptation of dengue-transmitting mosquitoes to colder places. This project develops and uses mathematical models and computational methods, including the novel Math-model Informed Neural Networks (MINN) based on emerging mathematics in mosquito-dengue biology. Proper management guidelines, identified through data-driven models, help healthcare professionals mitigate the burdens of dengue infection, thereby improving the quality of life for dengue-infected patients and their families. The outcomes of this project not only fundamentally advance the fields of mathematical biology and quantitative biology but also have a simultaneous broad and highly positive societal impact. In addition, this project offers extensive interdisciplinary research training opportunities for undergraduate and graduate students in mathematics and biology. The project will expand research and educational opportunities to various programs for students, as well as junior and senior researchers, and will incorporate the research into an interdisciplinary mathematical biology course.

This project will focus on three aims: (a) Develop Math-model Informed Neural Networks (MINN) capturing emerging mathematics in climate-dependent mosquito-dengue biology. (b) Analyze models and develop MINN-based methods to estimate 

## Key facts

- **NSF award ID:** 2527286
- **Awardee organization:** San Diego State University Foundation (CA)
- **SAM.gov UEI:** H59JKGFZKHL7
- **PI:** Naveen K Vaidya
- **Primary program:** 01002526DB NSF RESEARCH & RELATED ACTIVIT
- **All programs:** Artificial Intelligence (AI), Machine Learning Theory, Biotechnology
- **Estimated total:** $200,000
- **Funds obligated:** $200,000
- **Transaction type:** Standard Grant
- **Period:** 09/01/2025 → 08/31/2028

## Primary source

NSF Award Search: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2527286

## Citation

> US National Science Foundation, Award 2527286, Collaborative Research: eMB: Math-model Informed Neural Network (MINN) based on Emerging Mathematics in Mosquito-Dengue Biology. Retrieved via AI Analytics 2026-06-07 from https://api.ai-analytics.org/grant/nsf/2527286. Licensed CC0.

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