This research project aims to prototype and evaluate an intelligent garment featuring an adaptive splint that clinicians can dynamically control to address the treatment goals of individuals with neurodevelopmental disabilities who engage in self-injurious behavior. This novel device will facilitate sensorimotor interaction between the adaptive splint and the individual. Additionally, the garment will communicate with therapists to enhance their understanding of the individual's responses to treatment decisions and to predict and analyze attempts at self-injurious behavior. Self-injurious behaviors in minimally verbal individuals with neurodevelopmental disorders can lead to significant physical, emotional, social, and economic challenges. Behavioral interventions currently represent the most established approach to managing self-injurious behaviors. Presently, interventions for severe cases involve individuals wearing rigid splints on their arms, which help mitigate injury risk while still allowing the behavior to occur. If successful, this research is anticipated to improve the quality of life for both patients and clinicians alike. The adaptive garment prototype will feature an active split that can adjust its mechanical stiffness in real time with a clinician-in-the-loop feedback mechanism. This research initiative has several key interdisciplinary objectives: 1) to assess the effectiveness of the first active splint designed for behavioral interventions, drawing on d