# Use of Materials Derived From Cattle in Human Food and Cosmetics
> **Food and Drug Administration** · Final rule; adoption of interim final rule as final with amendments. · Published 2016-03-18 · Effective 2016-04-18 · 81 FR 14718
## Document
- **Document number:** 2016-06123
- **Category:** fda-food
- **Sub-agency:** Food and Drug Administration
- **Federal Register citation:** 81 FR 14718
- **CFR reference:** 21 CFR 189
- **Publication date:** 2016-03-18
- **Effective date:** 2016-04-18
- **HHS docket:** Docket No. FDA-2004-N-0188
## Abstract

The Food and Drug Administration (FDA or we) is issuing a final rule prohibiting the use of certain cattle material to address the potential risk of bovine spongiform encephalopathy (BSE) in human food, including dietary supplements, and cosmetics. We have designated the following items as prohibited cattle materials: Specified risk materials (SRMs), the small intestine from all cattle (unless the distal ileum has been removed), material from nonambulatory disabled cattle, material from cattle not inspected and passed, or mechanically separated (MS) (Beef). We are taking this action to minimize human exposure to certain cattle material that could potentially contain the BSE agent.

## Source
- [Federal Register document](https://www.federalregister.gov/documents/2016/03/18/2016-06123/use-of-materials-derived-from-cattle-in-human-food-and-cosmetics)
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