# Select Agent: Modified Junín Virus Vaccine Strain
> **Centers for Disease Control and Prevention** · Notification of determination. · Published 2024-12-26 · 89 FR 104888
## Document
- **Document number:** 2024-30568
- **Category:** public-health
- **Sub-agency:** Centers for Disease Control and Prevention
- **Federal Register citation:** 89 FR 104888
- **CFR reference:** 42 CFR 73
- **Publication date:** 2024-12-26
## Abstract

The Centers for Disease Control and Prevention (CDC), located within the Department of Health and Human Services (HHS), has determined that a previously excluded attenuated strain, Jun[iacute]n virus vaccine strain Candid No.1, has key attenuating mutations in the glycoprotein envelope at GP1 T168A and GP2 F427I. Revertants at either of these positions have increased pathogenicity and virulence. Therefore, Jun[iacute]n virus vaccine strain Candid No. 1 containing GP1 168T and/or GP2 427F is a select agent and is subject to the select agent and toxin regulations.

## Source
- [Federal Register document](https://www.federalregister.gov/documents/2024/12/26/2024-30568/select-agent-modified-junn-virus-vaccine-strain)
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