# Secondary Direct Food Additives Permitted in Food for Human Consumption; Milk-Clotting Enzymes
> **Food and Drug Administration** · Final rule. · Published 1997-11-03 · Effective 1997-11-03 · 62 FR 59281
## Document
- **Document number:** 97-29048
- **Category:** fda-food
- **Sub-agency:** Food and Drug Administration
- **Federal Register citation:** 62 FR 59281
- **CFR reference:** 21 CFR 173
- **Publication date:** 1997-11-03
- **Effective date:** 1997-11-03
- **HHS docket:** Docket No. 93F-0461
## Abstract

The Food and Drug Administration (FDA) is amending the food additive regulations to provide for the safe use of aspartic proteinase enzyme preparation produced by pure culture fermentation of Aspergillus oryzae modified by recombinant deoxyribonucleic (DNA) techniques to contain the gene for aspartic proteinase enzyme from Rhizomucor miehei for use as a milk-clotting enzyme in the production of cheese.

## Source
- [Federal Register document](https://www.federalregister.gov/documents/1997/11/03/97-29048/secondary-direct-food-additives-permitted-in-food-for-human-consumption-milk-clotting-enzymes)
---
*AI Analytics · CC0 1.0*