# Use of Ozone-Depleting Substances; Removal of Essential Use Designations; Confirmation of Effective Date
> **Food and Drug Administration** · Direct final rule; confirmation of effective date. · Published 2007-04-27 · Effective 2007-04-23 · 72 FR 20942
## Document
- **Document number:** E7-8043
- **Category:** other
- **Sub-agency:** Food and Drug Administration
- **Federal Register citation:** 72 FR 20942
- **CFR reference:** 21 CFR 2
- **Publication date:** 2007-04-27
- **Effective date:** 2007-04-23
- **HHS docket:** Docket No. 2006N-0416
## Abstract

The Food and Drug Administration (FDA) is confirming the effective date of April 23, 2007, for the direct final rule that appeared in the Federal Register of December 7, 2006 (71 FR 70870). The direct final rule amends the regulation to remove beclomethasone, dexamethasone, fluticasone, bitolterol, salmeterol, ergotamine tartrate, and ipratropium bromide, used in oral pressurized metered- dose inhalers, from the list of essential uses of ozone-depleting substances. None of these products is currently being marketed. This document confirms the effective date of the direct final rule.

## Source
- [Federal Register document](https://www.federalregister.gov/documents/2007/04/27/E7-8043/use-of-ozone-depleting-substances-removal-of-essential-use-designations-confirmation-of-effective)
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