# Drug overdose deaths: South Carolina, 12mo-ending October 2025
> **734 deaths** — Synthetic opioids, excl. methadone (T40.4)
## Observation
- **Location:** South Carolina (SC)
- **Period:** 12 months ending October 2025
- **Indicator:** Synthetic opioids, excl. methadone (T40.4)
- **Reported deaths:** 734
- **Predicted final:** 737
- **Data completeness:** 100%
- **Footnote:** Underreported due to incomplete data.
## Source
- [CDC VSRR Provisional Drug Overdose Death Counts](https://data.cdc.gov/dataset/xkb8-kh2a)
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