# Drug overdose deaths: United States, 12mo-ending October 2025
> **45154 deaths** — Opioids (T40.0-T40.4,T40.6)
## Observation
- **Location:** United States (US)
- **Period:** 12 months ending October 2025
- **Indicator:** Opioids (T40.0-T40.4,T40.6)
- **Reported deaths:** 45154
- **Predicted final:** 45848
- **Data completeness:** 100%
- **Footnote:** Underreported due to incomplete data.
## Source
- [CDC VSRR Provisional Drug Overdose Death Counts](https://data.cdc.gov/dataset/xkb8-kh2a)
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