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and Exchange Commission**\n\n**Washington,\nD.C. 20549**\n\n \n\n**FORM\n10-K**\n\n \n\n(Mark\nOne)\n\n \n\n☒\n\nAnnual\nReport Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934\n\n \n\nFor\nthe Fiscal Year Ended **December 31, 2025**\n\n \n\n \n \n \n\n☐\n\nTransition\nReport Under Section 13 or 15(d) of the Securities Exchange Act of 1934\n\n \n\nFor\nthe transition period from _________ to _________\n\n \n\n \n\nCommission\nFile Number **001-41461**\n\n \n\n**AINOS,\nINC.**\n\n \n\n(Exact\nname of registrant as specified in its charter)\n\n \n\n**Texas**\n \n**75-1974352**\n\n(State\nor other jurisdiction\n\nof\nincorporation or organization)\n\n \n\n(IRS\nEmployer\n\nIdentification\nNo.)\n\n \n \n \n\n**3050\nPost Oak Blvd, Suite 510-T80 Houston, TX**\n \n**77056**\n\n(Address\nof principal executive offices)\n \nZip\nCode\n\n \n \n \n\nIssuer’s\ntelephone number, including area code:\n \n**(281)898-6586**\n\n \n\nSecurities\nregistered under Section 12(b) of the Exchange Act.\n\n \n\n**Title\nof each class**\n** **\n**Trading\nSymbol(s)**\n** **\n**Name\nof each exchange on which registered**\n\nCommon\nStock\n \nAIMD\n \n\nThe\nNasdaq Stock Market LLC\n\n(Nasdaq\nCapital Market)\n\nCommon\nStock Purchase Warrants\n \nAIMDW\n \n\nThe\nNasdaq Stock Market LLC\n\n(Nasdaq\nCapital Market)\n\n \n\nSecurities\nregistered under Section 12(g) of the Exchange Act. None\n\n \n\nIndicate\nby check mark whether the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. ☐ Yes ☒\nNo\n\n \n\nIndicate\nby check mark whether the issuer is not required to file reports pursuant to Section 13 or 15(d) of the Exchange Act. ☐ Yes ☒\nNo\n\n \n\nIndicate\nby check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Exchange Act of 1934\nduring the past 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject\nto such filing requirements for the past 90 days. ☒ Yes ☐ No\n\n \n\nIndicate\nby check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule\n405 of Regulation S-T (§ 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant\nwas required to submit such files). ☒ Yes ☐ No\n\n \n\nIndicate\nby check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting\ncompany, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,”\n“smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.\n\n \n\n \nLarge\naccelerated filer\n☐\nAccelerated\nfiler\n☐\n\n \nNon-accelerated\nfiler\n☒\nSmaller\nreporting company\n☒\n\n \nEmerging\ngrowth company\n☐\n \n \n\n \n\nIf\nan emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying\nwith any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐\n\n \n\nIndicate\nby check mark whether the registrant has filed a report on and attestation to its management’s assessment of the effectiveness\nof its internal control over financial reporting under Section 404(b) of the Sarbanes-Oxley Act (15 U.S.C. 7262(b)) by the registered\npublic accounting firm that prepared or issued its audit report. ☐\n\n \n\nIf\nsecurities are registered pursuant to Section 12(b) of the Act, indicate by check mark whether the financial statements of the registrant\nincluded in the filing reflect the correction of an error to previously issued financial statements. ☐\n\n \n\nIndicate\nby check mark whether any of those error corrections are restatements that required a recovery analysis of incentive-based compensation\nreceived by any of the registrant’s executive officers during the relevant recovery period pursuant to §240.10D-1(b). ☐\n\n \n\nIndicate\nby check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). ☐ Yes ☒ No\n\n \n\nAs\nof June 30, 2025, the aggregate market value of the shares of common stock outstanding, other than shares held by persons who may be\ndeemed affiliates of the Registrant, computed by reference to the closing price of $2.83 for the Registrant’s common stock on June\n30, 2025, as reported on Nasdaq Capital Market, was approximately $4.4 million. Shares of common stock held by officers, directors and\neach shareholder owning 10% or more of the outstanding common stock have been excluded in that such persons may be deemed to be affiliates.\n\n \n\nAs\nof March 30, 2026, there were issued and outstanding 7,266,011 shares of the registrant’s common stock, par value $0.01, which\nis the only class of common or voting stock of the registrant.\n\n \n\n \n\n \n\n \n\n \n\n** **\n\n**TABLE\nOF CONTENTS**\n\n \n\n[PART I](#a_001)\n \n**3**"}